Results 151 to 160 of about 965,870 (302)

Interaction of infant mortality and fertility and the effectiveness of health and family planning programs [PDF]

The interaction of fertility and infant mortality is well established. Lower infant mortality can lead to lower fertility by reducing the need for replacement births. Conversely, birth spacing improves the chances of child survival. To find out how these
Barnum, Howard
core  

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Survival analysis of environmental determinants related to child mortality in Liberia. [PDF]

BMC Pediatr
Isabirye A, Poovendhree R.
europepmc   +1 more source

Statistics of Child Mortality [PDF]

BMJ, 1939
openaire   +2 more sources

MORTALITY DIFFERENTIAL, LABOR TAXATION AND GROWTH: WHAT DO WE LEARN FROM THE BARRO-BECKER MODEL? [PDF]

We revisit the seminal paper on endogenous fertility by Barro and Becker (1989) taking into account households' heterogeneity in terms of capital endowments, mortality differential and cost per surviving child.
Stefano Bosi, Thomas Seegmuller
core  

Generation of CCR4/CD7 Bispecific CAR‐T Cells Resistant to Fratricide and Exhaustion

Advanced Science, EarlyView.
The applications of CAR T‐cell therapy in T‐cell malignancies face limitations such as fratricide, effector‐cell exhaustion, and antigen‐escape. Herein, we developed fratricide‐ and exhaustion‐resistant CAR‐T cells that targeted CCR4 and CD7 simultaneously, with optional EGFRt safety switch. Additionally, scRNA‐seq unveiled new molecular targets, which
Sile Li, Yuanxin Li, Asif Rashid, Hong Kee Tan, Shing Chan, Man Yan Hui, Wilson Yau Ki Chan, Kee See Lam, Yinping Liu, Wenwei Tu, Wing Leung   +10 more
wiley   +1 more source

A hierarchical competing risks survival model in the study of child mortality in Bangladesh. [PDF]

Sci Rep
Haque N, Haque MA, Sadikeen SS, Uddin MJ.   +3 more
europepmc   +1 more source

Health outcomes in poor countries and policy options : empirical findings from demographic and health surveys [PDF]

Empirical studies on health at a disaggregate level-by socioeconomic group or geographic location-can provide useful information for designing poverty-focused interventions.
Wang, Limin
core  

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source