Results 181 to 190 of about 4,183,492 (391)

Calhm6 Governs Macrophage Polarization Through Chp1‐Camk4‐Creb1 Axis and Ectosomal Delivery in Inflammatory Responses

open access: yesAdvanced Science, EarlyView.
Calhm6 drives M2 macrophage polarization via the Chp1‐Camk4‐Creb1 axis, suppressing inflammation through calcium‐dependent ectosomal delivery. Calhm6 deficiency enhances M1 responses, boosting bactericidal activity but exacerbating tissue damage. LPS/IFNγ upregulate Calhm6 via Irf1, while IL‐4/Stat6 inhibits it, balancing immune outcomes.
Yanlong Xin   +14 more
wiley   +1 more source

Infant and Child Mortality in Andhra Pradesh: Analysing changes over time and between states [PDF]

open access: yes
Most countries of the world are reducing infant and child mortality too slowly to meet the Millennium Development Goal of a two-thirds reduction by 2015.
Masset, Edoardo, White, Howard
core   +1 more source

Midwives’ experiences of performing obstetric ultrasounds in antenatal care in eastern Ethiopia: Qualitative exploratory study

open access: yesWomen's Health
Background: In 2016, the World Health Organization recommended inclusion of an ultrasound scan as part of routine antenatal care to improve pregnancy outcomes.
Maleda Tefera   +3 more
doaj   +1 more source

Deacetylation of ACLY Mediates RNA M6A‐Modification of NOXA and Promotes Chemoresistance of Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
This study investigates the deacetylation of ACLY at K978 acts as a novel risk in colorectal cancer chemoresistance. The deacetylation of K978 induces ACLY relocation to the nucleus and promotes its binding to RBM15, a m6A methylation modification “writer”.
Jun Wen   +8 more
wiley   +1 more source

Child Mortality Reacts to Relative Prices [PDF]

open access: yes
This paper argues that, for a given average level of income per capita, the real currency depreciation has a negative impact on child survival, due to higher relative prices of tradable goods such as food and drug. This assumption is significantly tested
Christopher GRIGORIOU   +1 more
core  

Trends in child mortality in India

open access: yesIndian Pediatrics, 2013
To assess Indias recent trends in child mortality rates and disparities and identify ways to reduce child mortality and wealth-related health disparities, we analyzed three years of data from Indias National Family Health Survey related to child mortality.
openaire   +3 more sources

HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su   +13 more
wiley   +1 more source

How Macroeconomic Instability Lowers Child Survival [PDF]

open access: yes
The reduction of child mortality is one of the most universally accepted millennium goals. However, a significant debate came out on the means of reaching it and on its realism with regard to the situation of most of the least developed countries.
Catherine Korachais   +2 more
core  

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