Results 181 to 190 of about 966,714 (352)

HRS Degradation‐Induced Nicotinamide Deficiency in Placental Extracellular Vesicles Triggers Preeclampsia by Disrupting Maternal‐Fetal Immune Homeostasis

Advanced Science, EarlyView.
This study shows that lower NAM levels in PE‐derived pEVs correlate with disease severity. NAM‐deficient pEVs reduce Th1 and Th17 inhibition, leading to PE‐like symptoms. NAM in pEVs inhibits Th1 via SIRT1 and Th17 via macrophages. Reduced NAM in PE‐EVs is due to decreased HRS expression in trophoblasts, resulting from elevated HSP27.
Haiyi Fei, Yuhan Lin, Xiu Liu, Xiaohong Zhu, Xiaowen Lu, Zhan Shi, Fan Jia, Shiqian Xu, Ling Fang, Lingling Jiang, Songying Zhang   +10 more
wiley   +1 more source

Humility is critical in science communication: lessons from the UN's recent report on child mortality estimates. [PDF]

Glob Health Res Policy
Reidpath DD, Wahl B, Schwalbe N.
europepmc   +1 more source

Traditional Medicine Beliefs and Practices among Caregivers of Children under Five Years—The Child Health and Mortality Prevention Surveillance (CHAMPS), Western Kenya: A qualitative study

, 2022
Sarah Hawi Ngere, Victor Akelo, Ken Ondenge, Renée Ridzon, Peter Otieno, Maryanne Nyanjom, Richard Omore, Beth A. Tippett Barr   +7 more
openalex   +2 more sources

A Mussel‐Inspired Bioadhesive Patch to Selectively Kill Glioblastoma Cells

Advanced Science, EarlyView.
An innovative mussel‐inspired bioadhesive patch has been developed for post‐surgical glioblastoma treatment. The patch, which adheres strongly in biological environments, releases a localized treatment. This treatment, acting via reactive oxygen species, shows specific toxicity to glioblastoma cells.
Jose Bolaños‐Cardet, Sara Pugliese, Jordi Bruna, Daniel Ruiz‐Molina, Salvio Suárez‐García, Victor J. Yuste   +5 more
wiley   +1 more source

Reducing urban-rural disparities in maternal and child mortality in China: a 33-year analysis and projection to 2030. [PDF]

J Glob Health
Rao Z, Liu B, Li D, Qing Z, Lu Y, Yin D, Li S, Cheng K, Xiao Y, Dai Q.   +9 more
europepmc   +1 more source

Spatial Profiling Reveals Distinct Molecular and Immune Evolution of Mouse Lung Adenocarcinoma Precancers with or Without Carcinogen Exposure

Advanced Science, EarlyView.
Tumor evolution in lung adenocarcinoma is shaped by genetic alterations and spatial immune dynamics. By integrating whole‐exome sequencing, imaging mass cytometry, and spatial transcriptomics across two mouse models, this study reveals how mutational burden, immune infiltration, and cell–state interactions evolve during early and late carcinogenesis ...
Bo Zhu, Muhammad Aminu, Pingjun Chen, Jian‐Rong Li, Chuanpeng Dong, Chenyang Li, Yanhua Tian, Shao‐Wei Lu, Hong Chen, Chenxi Ma, Xin Hu, Jie Ye, Andrew Y. Liu, Beibei Huang, Frank R. Rojas, Parra Cuentas. Edwin Roger, Ou Shi, Monique B. Nilsson, Alissa Poteete, Khaja B. Khan, Wei Lu, Luisa M. Solis Soto, Junya Fujimoto, Cara Haymaker, Ignacio I. Wistuba, Zhubo Wei, Linghua Wang, Don L. Gibbons, Ken Chen, Alexandre Reuben, Jason M. Schenkel, John V. Heymach, Chao Cheng, Jia Wu, Jianjun Zhang   +34 more
wiley   +1 more source

Critical Response to the Comments on the Critical Issue of Infant and Child Mortality in Afghanistan. [PDF]

Health Sci Rep
Lippi G, Mattiuzzi C.
europepmc   +1 more source

Vitamin A Degradation and Dietary Adequacy: Modeled Effects on Dietary Adequacy, Child Mortality, and Cost-Effectiveness in Nigeria

Lauren Thompson, Michael Jarvis, Reina Engle‐Stone, Katherine P. Adams, Stephen A. Vosti   +4 more
openalex   +1 more source

Age at Marriage, Fertility and Infant-Child Mortality in a Lahore Suburb (Part I)

, 1976
Mohammad Afzal, Zubeda Khan, Naseer A. Chaudhry   +2 more
openalex   +2 more sources

LiST modelling with monitoring data to estimate impact on child mortality of an ORS and zinc programme with public sector providers in Bihar, India [PDF]

, 2018
A. Jayachandran, C. Harbour, Sanjeev Kumar, Manjula Singh   +3 more
openalex   +1 more source