Results 191 to 200 of about 4,183,492 (391)

Burden, Differential and Causes of Child Mortality in India (2010–2020): A Review

open access: yesPreventive Medicine: Research & Reviews
This review analyses the trends, prevalence, causes and disparities of child mortality in children up to 5 years of age in India using the latest data from the Sample Registration System and the National Family Health Survey.
Aninda Debnath, Chandrakant Lahariya
doaj   +1 more source

m6A‐Modified circRAPGEF1 Interaction with IGF2BP3 Promotes Hepatocellular Carcinoma Progression via Reprogramming Aspartate Metabolism

open access: yesAdvanced Science, EarlyView.
In hepatocellular carcinoma (HCC), the m6A‐modified circRAPGEF1 destabilizes ASS1 mRNA via competitive binding to IGF2BP3, driving aspartate metabolic reprogramming in liver cancer stem cells (LCSCs). This cascade enhances stemness properties and reduces sorafenib sensitivity in LCSCs, thereby identifying circRAPGEF1 as a promising therapeutic target ...
Juanyi Shi   +13 more
wiley   +1 more source

The Effect of Child Mortality on Fertility [PDF]

open access: bronze, 2001
Ahmad Kabir   +3 more
openalex   +1 more source

Integrated ‘Shield‐Spear’ Biological Patch for Fibrosis‐Free Bladder Reconstruction

open access: yesAdvanced Science, EarlyView.
Fibrosis‐free bladder reconstruction remains challenging. This study pioneers an integrated “shield‐spear” patch: The outer anionic hydrogel layer captures GATA6+ macrophages to suppress collagen overexpression, while the inner S100 aptamer‐engineered EVs target Schwann cells to downregulate the TGFβ/Smad pathway—inhibiting fibrosis with enhanced wound
Xiaoqi Wu   +14 more
wiley   +1 more source

The NSP5, ORF6 and NSP13 of SARS‐CoV‐2 Cooperate to Modulate Inflammatory Cell Death Activation

open access: yesAdvanced Science, EarlyView.
ZBP1 is capable of initiating a large cell death complex to induce programmed cell death during SARS‐CoV‐2 infection. However, SARS‐CoV‐2 can inhibit the activation of ZBP1‐mediated cell death by targeting key components of this complex. This suppression of ZBP1‐mediated cell death may account for the increased mortality observed in patients co ...
Huan Wang   +16 more
wiley   +1 more source

Social Impacts of Climate Change in Mexico: A municipality level analysis of the effects of recent and future climate change on human development and inequality [PDF]

open access: yes
This paper uses municipality level data to estimate the general relationships between climate, income and child mortality in Mexico. Climate was found to play only a very minor role in explaining the large differences in income levels and child mortality
Dorte Verner, Lykke E. Andersen
core  

Child mortality rate in ethiopia.

open access: yesIranian journal of public health, 2012
Ethiopia's childhood mortality has continued to decline although at a swift pace. The drop in urban childhood mortality decline, duration of breastfeeding is the principle reason for the overall decline in mortality trends in Ethiopia. Data from the Ethiopian Demographic and Health Surveys 2000 and 2005 were used.
openaire   +3 more sources

PCSK9 Loss‐of‐Function Disrupts Cellular Microfilament Network via LIN28A/HES5/JMY Axis in Neural Tube Defects

open access: yesAdvanced Science, EarlyView.
PCSK9 acts as a molecular chaperone promoting LIN28A lysosomal degradation. LIN28A elevates transcription factor HES5, increasing JMY expression. PCSK9 loss causes neural tube defects (NTDs) by disrupting the LIN28A/HES5/JMY axis, and high JMY disorganizes the neural progenitor cell microfilament network, leading to incomplete neural tube structure in ...
Xiaoshuai Li   +6 more
wiley   +1 more source

Poverty, Undernutrition, and Child Mortality: Some Inter-Regional Puzzles and their Implications for Research and Policy [PDF]

open access: yes
This paper examines the relationship between measures of income poverty, undernourishment, childhood undernutrition, and child mortality in developing countries.
Stephan Klasen
core  

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