Results 191 to 200 of about 4,625,605 (347)

The Regulatory Role of Iron Transporter SLC39A13 in Liver Fibrosis

Advanced Science, EarlyView.
SLC39A13/ZIP13, a newly discovered intracellular iron transporter, delivers iron to the ER/Golgi to catalyze procollagen hydroxylation during collagen maturation. Here, we systematically characterize the cell type‐specific functions of ZIP13 across distinct hepatic cell populations, and identify hepatic stellate cell‐specific ZIP13 as a promising and ...
Shanshan Guo, Yalin Wang, Binyu Lu, Yu Zhang, David M. Frazer, Bing Zhou   +5 more
wiley   +1 more source

Investigating the determinants of under-five child mortality in Türkiye: the role of inequality in access to healthcare. [PDF]

Global Health
Kizilkaya S, Durgun B, Durgun F.
europepmc   +1 more source

Statistics of Child Mortality [PDF]

BMJ, 1939
openaire   +2 more sources

Targeting the GPX4–FUNDC1 Interaction with Magnesium Lithospermate B Attenuates Sepsis‐Associated Lung Injury

Advanced Science, EarlyView.
The diagram depicts the endothelial‐protective mechanism of magnesium lithospermate B (MLB) in sepsis‐associated lung injury. MLB binds GPX4 at Gly79, disrupts its interaction with FUNDC1, prevents mitophagy‐mediated GPX4 degradation, restores mitophagic flux, reduces ROS, and limits ferroptosis.
Zhixi Li, Chang Liu, Zhaoxue Ma, Dongyou Zheng, Renkai Wang, Yongjing Yu, Guangmin Chen, Chenglong Li, Yue Bu, Hang Cao, Bing Zhang   +10 more
wiley   +1 more source

Determinants of multiple modes of failure in child mortality in Bangladesh: fine and gray modeling approach. [PDF]

J Health Popul Nutr
Tithy TA, Islam MA.
europepmc   +1 more source

Lowering Child Mortality in Poor Countries: The Power of Knowledgeable Parents [PDF]

Why do over 20% of children die in some poor countries, while in others only 2% die? We examine this question using survey data covering 278,000 children in 45 low-income countries.
Peter Boone, Zhaoguo Zhan
core  

SLC2A3‐Mediated Lactate Metabolism Promotes Lung Cancer Bone Metastasis by Modulating P53 Lactylation and Immune Evasion

Advanced Science, EarlyView.
SLC2A3 derived lactate promotes metastasis through p53 lactylation at K120 and osteoclast differentiation. Pharmacological inhibition of SLC2A3 upregulates PD‐1 expression on CD8+ T cells via lactate induced p53 lactylation, which modulates immune evasion. ABSTRACT Bone metastasis is a devastating consequence of lung cancer.
Yi Ding, Yuying Tian, Wenjie Ren, Xianglin Hu, Mengjuan Li, Bei Liu, Chen chen, Yunhan Lu, Lei Li, Wangjun Yan, Kun Li   +10 more
wiley   +1 more source

Distributional dynamics of child mortality in Africa: quantile evidence from economic, environmental, and demographic transitions. [PDF]

Front Public Health
Ridwan M, Ko J, Antor ZA, Fakher HA, Akther A, Leung CK, Kelly AM, Ming WK.   +7 more
europepmc   +1 more source

Promotion of DFU Wound Healing via BRG1–COL16A1 Axis in Fibroblasts

Advanced Science, EarlyView.
In normal wound healing, transcription factor BRG1 is upregulated and binds the COL16A1 promoter to enhance its expression, promoting fibroblast proliferation, migration, contraction, extracellular matrix deposition, and granulation tissue formation, thus accelerating wound closure.
Penghui Wang, Jiaming Sun, Ying Wang, Bichen Ren, Yuxin Liu, Yunhan Liu, Liang Chen, Lu Yu, Tao Dai, Li Yu, Zhihui Dong   +10 more
wiley   +1 more source

Association of Previne Brasil Program with prenatal care and maternal-child mortality. [PDF]

Rev Saude Publica
Arato CVB, Guerra LM, Probst LF, Pereira AC.   +3 more
europepmc   +1 more source