Advanced Science, EarlyView.A tetranitrogen‐coordinated single‐atom manganese catalyst (SMC) is fabricated with outstanding sonosensitization efficiency and multi‐enzyme‐like catalytic properties. To enable better targeting of M1 macrophages, hyaluronic acid (HA) is applied to modify the surface of SMC, yielding SMC‐HA nanozymes.
Qiaofei Chen +14 more
wiley +1 more source
Does the Mortality Decline Promote Economic Growth? [PDF]
This paper analyzes qualitatively and quantitatively the e ects of declining mortality rates on fertility, education and economic growth. The analysis demonstrates that if individuals are prudent in the face of uncertainty about child survival, a decline
Sebnem Kalemli-Ozcan
core
A multilevel event history analysis of the effects of grandmothers on child mortality in a historical German population (Krummhörn, Ostfriesland, 1720-1874) [PDF]
, 2002 Jan Beise, Eckart Voland
openalex +1 more source
The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset
Advanced Science, EarlyView.The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng +22 more
wiley +1 more source
Determinants of infant and child mortality in Zimbabwe: Results of multivariate hazard analysis [PDF]
This study addresses important issues in infant and child mortality in Zimbabwe. The objective of the paper is to determine the impact of maternal, socioeconomic and sanitation variables on infant and child mortality. Results show that births of order 6+
Jeroen K Van Ginneken, Joshua Kembo
core
CircSMEK1 Suppresses HCC via the hnRNPK‐IGF2‐AKT Axis: A Diagnostic Biomarker and Therapeutic Target
Advanced Science, EarlyView.CircSMEK1 is downregulated in MASH/HCC and predicts poor prognosis. It suppresses tumor progression by promoting hnRNPK ubiquitination and inhibiting the IGF2/PI3K/AKT axis, while its loss activates immunosuppressive cancer‐associated fibroblasts. Serum circSMEK1 serves as a non‐invasive diagnostic biomarker, and its restoration potently inhibits HCC ...
Peilan Guo +15 more
wiley +1 more source
Interaction of infant mortality and fertility and the effectiveness of health and family planning programs [PDF]
The interaction of fertility and infant mortality is well established. Lower infant mortality can lead to lower fertility by reducing the need for replacement births. Conversely, birth spacing improves the chances of child survival. To find out how these
Barnum, Howard
core
A comparison of Child-Pugh, APACHE II and APACHE III scoring systems in predicting hospital mortality of patients with liver cirrhosis [PDF]
, 2003 Constantinos Chatzicostas +7 more
openalex +1 more source
Advanced Science, EarlyView.This study reveals that ADAR1, an RNA‐editing enzyme, fine‐tunes immune responses in the placenta by preventing the accumulation of immunogenic double‐stranded RNAs (dsRNAs) from interferon‐stimulated genes. The loss of ADAR1 in the placenta leads to excessive interferon signaling restricted to the junctional zone, disrupting placental development and ...
Xiaogang Chen +7 more
wiley +1 more source