Results 231 to 240 of about 4,183,492 (391)

Novel Evolutionarily Conserved Oncogene COA4 is Driven by KRAS Mutant and Promotes Cancer Metastasis Through Dual Mitochondrial Metabolism‐Dependent and ‐Independent Mechanisms

open access: yesAdvanced Science, EarlyView.
In KRAS‐mutant tumors, KRAS transcriptionally upregulates COA4 via the PI3K/AKT/E2F1 axis, promoting metastasis. Mechanistically, COA4 enhances tumor cell migration through dual pathways: within mitochondria, it boosts oxidative phosphorylation; in the cytoplasm, it binds and activates CDC42 to stimulate pseudopodia formation.
Xingzhao Ji   +14 more
wiley   +1 more source

A Multilevel Approach to Explain Child Mortality and Undernutrition in South Asia and Sub-Saharan Africa [PDF]

open access: yes
While undernutrition among children is very pervasive both in Sub- Saharan Africa and South Asia, child mortality is rather low in South Asia. In contrast to that Sub-Saharan African countries suer by far the worst from high rates of child mortality ...
Kenneth Harttgen, Mark Misselhorn
core  

Big Data and AI‐Powered Modeling: A Pathway to Sustainable Precision Animal Nutrition

open access: yesAdvanced Science, EarlyView.
This review summarizes the current landscape of big data and AI‐powered modeling in animal nutrition, covering techniques including intelligent data acquisition, data augmentation, explainable machine learning, heuristic algorithms, and life cycle assessment‐based sustainability evaluation.
Shuai Zhang   +3 more
wiley   +1 more source

Water and sanitation to reduce child mortality : the impact and cost of water and sanitation infrastructure [PDF]

open access: yes
Using household survey data, this paper estimates the mortality impact of improved water and sanitation access in order to evaluate the potential contribution of water and sanitation investment toward achieving the child mortality targets defined in ...
Fink, Gunther, Gunther, Isabel
core  

Armed conflict and child mortality in Africa: a geospatial analysis

open access: yesThe Lancet, 2018
Z. Wagner   +5 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy