Results 241 to 250 of about 4,183,492 (391)

Association of Selected Risk Factors with Variation in Child and Adolescent Firearm Mortality by State [PDF]

, 2004
Judy Murnan, Joseph A. Dake, James H. Price   +2 more
openalex   +1 more source

Discovery of a Baloxavir‐Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo

Advanced Science, EarlyView.
Current herpesvirus treatments targeting the viral DNA polymerase are limited by toxicities and drug resistance. Novel compounds inhibiting the nuclease activity of the herpes simplex virus 1 (HSV‐1) terminase complex, required for viral genome packaging, have been identified.
Sabina Andreu, Kai Tang, Jiahui Zhou, Gabriel Pino‐Peco, Nerea López‐Carrobles, Raquel Bello‐Morales, Daniel Galdo‐Torres, Lina Zhang, Federico Gago, José Antonio López‐Guerrero, Xinyong Liu, Peng Zhan, Luis Menéndez‐Arias   +12 more
wiley   +1 more source

Changes in child mortality and population health following 10 years of health systems strengthening in rural Madagascar: A longitudinal cohort study. [PDF]

PLoS Med
Garchitorena A, Miller AC, Razanadranaivo HL, Rakotonirina L, Barriault SA, Razafinjato B, Kotchofa JA, Rafenoarimalala F, Rakotonanahary RJL, Ihantamalala FA, Evans MV, Tolojananahary AT, Ramanandraitsiory V, Tsitinomen'nyaina A, Ralaivavikoa FA, Raza-Fanomezanjanahary EM, Randriamanambintsoa M, Andrianambinina S, Yasmine LL, Murray MB, Rich ML, Cordier LF, Finnegan KE, Bonds MH, Randriamanantany ZA.   +24 more
europepmc   +1 more source

Air Pollution and Child Mortality: A Time-Series Study in Sao Paulo, Brazil

, 2001
Gleice M.S. Conceição, Simone Georges El Khouri Miraglia, Humberto S. Kishi, Paulo Hilário Nascimento Saldiva, Júlio M. Singer   +4 more
openalex   +1 more source

Microphysiological Solid Tumor Models in Hydrogel Beads for CAR T Cell Immunotherapy Evaluation

Advanced Science, EarlyView.
The complex physical and biochemical barriers of the tumor microenvironment are major triggers of immune exclusion. Here, a 3D micrometastasis model is developed to mimic key microenvironmental cues, enabling in vitro evaluation of chimeric antigen receptor (CAR) T cell immunotherapy. Abstract Micrometastases are challenging to resect surgically and to
Xuan Peng, Željko Janićijević, Liliana R. Loureiro, Lydia Hoffmann, Poh Soo Lee, Isli Cela, Benjamin Kruppke, Alexandra Kegler, Anja Feldmann, Ielizaveta Gorodetska, Anja Madleine Markl, Anna Dubrovska, Anne Kathrin Offermann, Michael Bachmann, Larysa Baraban   +14 more
wiley   +1 more source

Association of birth defects during the perinatal period with child mortality under 5 years. [PDF]

Front Pediatr
Xie D, Wei J, Xiong L, Zhu H, Peng X, Li B, Zou K.   +6 more
europepmc   +1 more source

SNORA58 Facilitates Radioresistance via Suppressing JNK1‐Mediated Ferroptosis in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
In ESCC patients, SNORA58 exhibits heterogeneous expression patterns. Its aberrant overexpression stabilizes CTCF by inhibiting ubiquitin‐mediated degradation, leading to the attenuation of JNK1‐mediated ferroptosis induced by radiotherapy through disruption of intracellular iron homeostasis, and ultimately contributes to radioresistance ...
Yinli Zheng, Fangyi Liu, Yuhua Huang, Yanfen Feng, Xia Yang, Jinjun Wu, Xin Yang, Xuanhao Lin, Lives Jiang, Tingting Zeng, Yan Li, Xinyuan Guan, Yuanyuan Wang, Chunyan Chen, Jingping Yun   +14 more
wiley   +1 more source

Utilizing Proteolytic‐Resistant Nano‐Short Peptide Based on Naphthyl Tail‐Anchored to Combat Bacterial Infections

Advanced Science, EarlyView.
Antimicrobial peptides (AMPs) show potential as alternatives to antibiotics for bacterial infections; however, their susceptibility to proteases limits wider application. In this study, N4 nanofibers are constructed by integrating anti‐enzymolysis motif into the self‐assembly system triggered by naphthyl‐anchored.
Xi Yan, Yinfeng Lyu, Yi Liu, Jianping Ren, Yue Zhao, Licong Zhang, Anshan Shan   +6 more
wiley   +1 more source

The role of seasonal malaria chemoprevention in the effect of azithromycin on child mortality: A secondary analysis of the CHAT cluster randomized clinical trial. [PDF]

PLOS Glob Public Health
Gebreegziabher EA, Ouattara M, Bountogo M, Coulibaly B, Boudo V, Ouedraogo T, Lebas E, Hu H, O'Brien KS, Hsiang MS, Glidden DV, Arnold BF, Lietman TM, Sié A, Oldenburg CE.   +14 more
europepmc   +1 more source

Randomized trial of vitamin supplements in relation to transmission of HIV-1 through breastfeeding and early child mortality

, 2002
Wafaie Fawzi, Gernard Msamanga, David J. Hunter, Boris Renjifo, Gretchen Antelman, Heejung Bang, Karim Manji, Saidi Kapiga, Davis Mwakagile, Max Essex, Donna Spiegelman   +10 more
openalex   +1 more source