Results 61 to 70 of about 2,724,440 (240)

Child and adult mortality in Zimbabwe, 1980-2005 [PDF]

open access: yes, 2011
This research applies direct and indirect methods to data from censuses and Demographic and Health Surveys to derive empirical estimates of the level and trends of child and adult mortality in Zimbabwe from 1980 to ...
Marera, Double-Hugh
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Education Policy and Under-Five Survival in Uganda: Evidence from the Demographic and Health Surveys

open access: yesSocial Sciences, 2016
This study seeks to examine the influence of mothers’ schooling accomplishments on child mortality outcomes by exploiting the exogenous variability in schooling prompted by the 1997 universal primary education (UPE) policy in Uganda.
Marshall Makate
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

The role of ‘hidden’ community volunteers in community-based health service delivery platforms: examples from sub-Saharan Africa [PDF]

open access: yesGlobal Health Action, 2015
Community-based research on child survival in sub-Saharan Africa has focussed on the increased provision of curative health services by a formalised cadre of lay community health workers (CHWs), but we have identified a particular configuration, that ...
Natalie Leon   +8 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

Levels and trends in child mortality

open access: yes, 2010
The United Nations Inter-agency Group for Child Mortality Estimation (UN-IGME) updates child mortality estimates annually for monitoring progress. This report presents the UN-IGME's latest estimates of under-five, infant and neonatal mortality and ...
World Health Organization   +3 more
core  

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

SOCIOECONOMIC INEQUALITIES, WATER, SANITATION, HYGIENE AND DIARRHEAL DISEASE AMONG CHILDREN UNDER FIVE YEARS IN INDONESIA

open access: yesJurnal Berkala Epidemiologi
Background: Diarrheal diseases are still a serious digestive tract infection in Indonesia. The geographical areas with lower socioeconomic inequalities and water, sanitation and hygiene (WASH) contribute to incline diarrheal disease among children under ...
Erni Astutik, Tika Dwi Tama
doaj   +1 more source

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