Results 151 to 160 of about 578 (190)

Impact of the pancreatic enzyme replacement therapy (PERT) shortage on prescribing in England: Analysis of national data

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Pancreatic enzyme replacement therapy (PERT) is essential for the management of pancreatic exocrine insufficiency. Since June 2023, the United Kingdom has been affected by a global shortage of PERT. We investigated the impact of this shortage on national prescribing trends for Creon, Nutrizym, Pancrex and Pangrol.
Teena S. Varghese   +6 more
wiley   +1 more source

Magnetoelastic Cell Monitoring System for Evaluating the Effects of Surface Chemistry on the Performance of Mesenchymal Stem Cell Growth

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT The recent clinical adoption of cell therapies has increased the need for more efficient, robust, and reproducible manufacturing technologies. Human mesenchymal stromal cells (hMSCs), a major component of the cell and immunotherapeutic market, remain challenging to manufacture at scale because they require surface attachment and are highly ...
William S. Skinner   +7 more
wiley   +1 more source

Translating Blue Light Stimulation From Batch to Perfusion: Process and Intracellular Metabolic Analysis

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Improving cell‐specific productivity remains a central objective in biopharmaceutical manufacturing. In this study, the effect of blue light illumination on IgG1‐producing CHO DP‐12 cells was systematically evaluated across batch, fed‐batch, and perfusion cultivations in controlled 3 L bioreactor systems.
Stefanie Föller   +2 more
wiley   +1 more source

Model‐Driven Monitoring and Parameter‐Based Development of an Escherichia coli Fed‐Batch Process for Production of a Fab Antibody Fragment Across Scales

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Maintaining consistent cellular physiology during bioprocess scale‐up or scale‐down is key to developing robust processes. However, the reliability of scale‐down bioreactor systems remains debated. Although the calibration of physiological parameters in mechanistic models across scales has been proposed as a scale‐down strategy, few studies ...
Fabian Schröder‐Kleeberg   +8 more
wiley   +1 more source

Reprogramming tumor immune microenvironment by ultrasound‐responsive nanoplatforms for enhanced cancer immunotherapy

open access: yesBMEMat, EarlyView.
Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao   +4 more
wiley   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

open access: yesBMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo   +9 more
wiley   +1 more source

Editorial focused issue ‘The role of nutrition in child and adolescent onset mental disorders’

European Child & Adolescent Psychiatry, 2017
Contains fulltext : 181897.pdf (Publisher’s version ) (Closed access)
Lambregts-Rommelse, N.N.J.   +1 more
openaire   +3 more sources

Behavior Management

Journal of Learning Disabilities, 1978
This essay explores the potential use of nutrition therapy in behavior management programs. It is suggested that children possessing behavioral disorders will not be capable of learning according to their potential and that nutrition therapy should be considered, along with other behavior management strategies, in rehabilitative programs.
openaire   +2 more sources

Progressive Weakness and Hypoglycemia in a Child With Selective Eating: A Nutritional Mimic of a Fatty Acid Oxidation Disorder

Journal of Child Neurology
Severe selective eating in children can lead to clinically important nutritional deficiencies. We report a 5-year-old boy with autism spectrum disorder who presented with progressive weakness and hypoglycemia mimicking a fatty acid oxidation disorder (FAOD).
Kengo Kora, Minako Ide, Takeo Kato
openaire   +1 more source

Management of a Child With Nutritional Rickets, Multiple Cavities, Enamel Hypoplasia, and Reactive Attachment Disorder

Journal of Pediatric Health Care, 2015
Donna Hallas   +4 more
openaire   +2 more sources

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