Results 181 to 190 of about 58,566 (300)

Child sexual exploitation and abuse: considerations of cultural differences in policy and legislation. [PDF]

Front Public Health
Young A, Mustafa MC, Rozubi NBC, Mat Rani NH, Wismayanti Y, Woodlock D, Singh S, O'Leary P, Salter M.   +8 more
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Gender-Responsive Macro-Level Policies and Women's Economic Empowerment in Sub-Saharan Africa: An Evidence and Gap Map. [PDF]

Campbell Syst Rev
Nyan CP, Manuh T, Oppong SA, Oppong M, Danso-Mensah K, Letsa I, Badu-Ansah NE, Sarfo Ameyaw D.   +7 more
europepmc   +1 more source

Nanocellulose Alleviates Intrahepatic Cholestasis of Pregnancy via Gut Microbiota‐Mediated Bile Acid Homeostasis

Advanced Science, EarlyView.
Nanocellulose, derived from microcrystalline cellulose (MCC) through sulfuric acid hydrolysis or mechanical grinding to produce CNC or CNF, was tested in a rat ICP model. Particularly, CNF improved gut microbiota composition, reduced secondary bile acid metabolism, and restored bile acid homeostasis through modulation of the gut–liver axis.
Muhua Yu, Hongjie Dai, Xiaocui Zhong, Qibin Li, Hui Yuan, Yang Yang, Daiyong Huang, Lei Zhang, Rui Ran, Tian He, Yuanzhi Huang, Silas Villas‐Boas, Sergey Tumanov, Richard D. Cannon, Boris Novakovic, Richard Saffery, Yuhao Zhang, Xiaojing Dong, Ting‐Li Han   +18 more
wiley   +1 more source

Diphtheria seroprotection among Indonesian children: Community Health Surveys Riskesdas 2007, 2013 and 2018. [PDF]

PLoS One
Hartanti MD, Sunarno S, Panjaitan NSD, Hasugian AR, Dewi RM, Handayani S, Maha MS, Fadilah TF, Fairuza F, Ningrum N, Sari M, Setiati D, Aziza NN, Devita A, Adriani D, Samira J, Lestari CSW.   +16 more
europepmc   +1 more source

Nigra‐Subthalamic Dopaminergic Circuitry Modulates and Represents Distinct Pain Modality in Physiological and Pain States in Mice

Advanced Science, EarlyView.
Nigral dopaminergic (DA) neurons modulate and represent pain with a preference to a particular modality (mechanical) and laterality (contralateral), which are controlled by nigral GABAergic neurons. The pain modulation is mimicked by the nigro‐subthalamic projection and its downstream neurons, involving D2‐like receptors.
Ying Ji, Shuyi Li, Jiaqi Zhang, Xiang‐Ying Xu, Cui Yin, Mu Niu, Danyang Liu, Yanyu Jiang, Yong Niu, Su Liu, Bin Zhang, Guiyun Cui, Chunyi Zhou, Cheng Xiao   +13 more
wiley   +1 more source

Release notice - Updated child protection legislation review with focus on Indigenous rights and data sharing, Canada. [PDF]

Health Promot Chronic Dis Prev Can
europepmc   +1 more source

Frontline practitioners' perspective of the implementation of child protection laws and prevention of violence against children in Maputo, Mozambique. [PDF]

Glob Health Action
Nhassengo S, Ocuane Matsinhe S, Jethá E, Sengoelge M, Laflamme L, Kulane A.   +5 more
europepmc   +1 more source

Icariin Enhances the Enzymatic Activity of N‐acetylgalactosaminidase to Augment Akkermansia Abundance in Gut Microbiota for Improved PD‐1 Blockade Efficacy in Tumor Suppression

Advanced Science, EarlyView.
Icariin promoted the growth of Akk by enhancing the activity of N‐acetylgalactosaminidase (Amuc_0920), which enhanced mucin utilization and provided a favorable nutrient environment for bacterial growth. This icariin‐mediated enrichment of Akk further reshaped the tumor microenvironment and promoted CD8+ T cell infiltration, ultimately synergizing with
Shuangying Qiao, Liu Yang, Haibang Hao, Qiuxia Ding, Feng Ding, Zheng Chen, Jinfang Zhang, Yun He, Meng Li, Jun Xu, Chao Wang, Aiping Lu, Fangfei Li   +12 more
wiley   +1 more source

First use of Trumenba (MenB-fHbp) vaccine to control a nursery outbreak of serogroup B invasive meningococcal disease involving children previously immunised with Bexsero (4CMenB), England, November 2023. [PDF]

Euro Surveill
Foster K, Heymer EJ, Campbell H, Wilson E, Baldasera J, Lucidarme J, Clark SA, Bai X, Ahmad S, Borrow R, Ladhani SN.   +10 more
europepmc   +1 more source