Results 111 to 120 of about 2,960,828 (297)
Deep whole genome sequencing of epileptogenic brain lesions
Abstract Objective Malformations of cortical development and low‐grade epilepsy‐associated tumors often cause drug‐resistant lesional focal epilepsy (LFE) amenable to surgical treatment. Genetic testing of resected brain tissue can provide diagnostic and mechanistic information and may eventually support personalized treatment approaches.
Christian M. Boßelmann +17 more
wiley +1 more source
Transcriptomic analysis reveals distinct expression patterns in focal cortical dysplasia
Abstract Objective Focal cortical dysplasia (FCD) is a common cause of drug‐resistant epilepsy in children and adults and exhibits substantial clinical and histopathological heterogeneity. However, morphological classification alone does not fully explain variability in epileptogenicity, disease severity, or treatment response.
Shivani Sonawane +20 more
wiley +1 more source
Introduction: Gender bias is strikingly apparent in educational access, employment avenues and representation in the field of politics. In fact violation of the rights of a girl child is rampant and this extends to the whole spectrum from foeticide to ...
Amit Patel +4 more
doaj
Status epilepticus: Updates on mechanisms and treatments
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley +1 more source
Abstract Objective Genetic epilepsies in childhood are highly heterogeneous, and approaches to identify shared biological mechanisms across distinct genetic etiologies remain limited. We aimed to investigate whether genes associated with pediatric genetic epilepsies in our heterogeneous cohort converge on common functional pathways.
Laura Hecher +11 more
wiley +1 more source
CHDS Supports Fusion Centers Leaders Participate in Child Sex Trafficking Workshop [PDF]
Fusion centers could serve as a central hub in assisting law enforcement fight child sex trafficking. That was one recommendation stemming from a joint meeting of IACP's Child Sex Trafficking Advisory Working Group and Fusion Center Stakeholders ...
Issvoran, Heather
core +1 more source
Exploring Trends in Federal Sex Trafficking Cases
Sex trafficking is quickly becoming one of the most prevalent issues in the realm of criminal justice and society in general. There are more slaves in the world today than at any other point in history, and this horrific crime is affecting the most ...
Taylor, Rachel
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Abstract Objective To determine the genetic diagnostic yield, characterize the clinical and genetic landscape, and evaluate long‐term epilepsy, neurodevelopmental, and survival outcomes in a strictly defined cohort of neonatal‐onset developmental and epileptic encephalopathy (DEE).
Júlia Sala‐Coromina +21 more
wiley +1 more source
Abstract Gender inequality remains widespread in the film and television production industry, yet it is seldom examined in relation to backstage working environments. This article integrates on‐screen and off‐screen perspectives to investigate the working lives of Chinese actresses.
Yajie Li, Yuhao Ding
wiley +1 more source
: In recent years, sex trafficking awareness and intervention have skyrocketed in the United States. The 2016 Polaris Hotline Statistics Sheet reports a drastic increase of reported sex trafficking cases over the span of four years, with only 3,409 cases
core

