Results 171 to 180 of about 495,028 (294)

Coping with the toll of child sexual abuse investigations. [PDF]

open access: yesFront Psychol
Easton L   +3 more
europepmc   +1 more source

Performance of the 5‐SENSE score in a pediatric and young adult cohort of 100 consecutive stereoelectroencephalography cases

open access: yesEpilepsia, EarlyView.
Abstract This study assesses the validity of the 5‐SENSE score in a cohort of pediatric patients with epilepsy and evaluates associations between the score, ancillary testing, and surgical outcomes. We retrospectively calculated the 5‐SENSE score in a single‐center predominantly pediatric cohort and calculated the sensitivity and specificity for ...
Lindsey Trank   +7 more
wiley   +1 more source

Effects of fenfluramine and sigma‐1‐dependent pharmacological and genetic modulation in a mouse kindling model

open access: yesEpilepsia, EarlyView.
Abstract Objective Sigma‐1 is a chaperone protein that serves as a key homeostatic regulator, implicated in neuronal excitability and seizure control. Positive allosteric modulators offer a use‐dependent means to enhance Sigma‐1 activity, potentially with favorable tolerability compared to direct agonists.
Eva‐Lotta von Rüden   +5 more
wiley   +1 more source

Febrile status epilepticus and epileptogenesis: The FEBSTAT study

open access: yesEpilepsia Open, EarlyView.
Abstract The multicenter FEBSTAT study (Consequences of Prolonged Febrile Seizures in Childhood: https://grantome.com/grant/NIH/R37‐NS043209‐12; PI S. Shinnar) examined the outcome of febrile status epilepticus (FSE) in over 200 prospectively enrolled infants, with many followed for 10 years after FSE.
Darrell V. Lewis   +14 more
wiley   +1 more source

Status epilepticus: Updates on mechanisms and treatments

open access: yesEpilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

The Global Epilepsy Needs Study (GENS): A mixed‐methods, multi‐country exploration of the unmet psychosocial and everyday needs of people with epilepsy

open access: yesEpilepsia Open, EarlyView.
Abstract Objective While epilepsy research has largely focused on medical management and clinical outcomes, less attention has been given to the unmet psychosocial and everyday needs of people with epilepsy (PWE), particularly in low‐ and middle‐income countries.
Gus A. Baker   +52 more
wiley   +1 more source

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