Results 51 to 60 of about 640,218 (357)

Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes

Advanced Science, EarlyView.
This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang, Meiyun Wang, Peng Zhang, Jingliang Cheng, Longjiang Zhang, Wenzhen Zhu, Shijun Qiu, Zuojun Geng, Guangbin Cui, Yongqiang Yu, Weihua Liao, Xi‐Nian Zuo, Hui Zhang, Bo Gao, Xiaojun Xu, Tong Han, Zhenwei Yao, Quan Zhang, Feng Liu, Qiang Xu, Jiayuan Xu, Jilian Fu, Nana Liu, Yuan Ji, Jie Tang, Lining Guo, Mengge Liu, Xiaoxiao Xiao, Xiaoxuan Liu, Wei Li, Caihong Wang, Wei Wei, Dapeng Shi, Su Lui, Zhihan Yan, Feng Chen, Jing Zhang, Wen Shen, Yanwei Miao, Dawei Wang, Jia‐Hong Gao, Yunjun Yang, Kai Xu, Junfang Xian, Bing Zhang, Xiaochu Zhang, Zhaoxiang Ye, Le Yu, Wen Qin, Meng Liang, Chunshui Yu, the CHIMGEN Consortium   +51 more
wiley   +1 more source

CHILD SEXUAL ABUSE: ISSUES OF ADMISSIBILITY

Indian Journal of Psychiatric Nursing, 2015
Child Sexual Abuse is prevalent in India as in many other countries and there is a growing concern to understand its dimensions and complexities. There is a large child population (19% of the total population) in India and a large percentage of this ...
K.N. Jayanthi
doaj   +1 more source

Updated Trends in Child Maltreatment, 2013. [PDF]

, 2015
New national data for 2013 show continued declines in child maltreatment, after a one year discontinuity (2012) in which some rates briefly increased.
Finkelhor, David, Jones, Lisa M., Saito, Kei   +2 more
core   +1 more source

Maternal and child reflective functioning in the context of child sexual abuse: pathways to depression and externalising difficulties

European Journal of Psychotraumatology, 2016
Background Sexual abuse is a well-recognised risk factor for child psychopathology. Little is known regarding whether child and maternal mentalization can be considered a potential resource or protective factor in this context, respectively, mediating or
K. Ensink, Michaël Bégin, L. Normandin, P. Fonagy   +3 more
semanticscholar   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Multifaceted Glance on Childhood Sexual Abuse and Incest [PDF]

Psikiyatride Güncel Yaklaşımlar, 2018
An experience of domestic violence can lead to permanent physical, mental, and psychological harms, whether the child is a direct victim or a witness. Although having no standard definition, it is generally agreed that childhood sexual abuse and incest ...
Aslihan Okan Ibiloglu, Abdullah Atli, Remzi Oto, Mustafa Ozkan   +3 more
doaj   +1 more source

Investigation of Mothers' Childhood Trauma and Their Relationships with Their Children

Yüzüncü Yıl Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2023
This study aimed to examine mothers' childhood trauma situations and their relations with their children. A relational screening model was used in this research. The study group of the research consisted of 250 mothers.
Zeynep Nur Aydın Kılıç, Fatime Aksu, Aslı Balcı, Zeynep Kishalı   +3 more
doaj   +1 more source

Updated Trends in Child Maltreatment, 2010. [PDF]

, 2011
Even in the midst of continuing difficult economic times, 2010 national statistics showed no increase in child maltreatment. Overall substantiated child maltreatment actually declined 1% from 2009 to 2010, including a 3% decline in sexual abuse and
Finkelhor, David, Jones, Lisa M., Shattuck, Anne M.   +2 more
core   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, EarlyView.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

Childhood Sexual Abuse [PDF]

Psikiyatride Güncel Yaklaşımlar, 2009
Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse ...
Evrim Aktepe
doaj