Results 51 to 60 of about 495,028 (294)
Safeguarding children and young people from sexual exploitation (consultation document) [PDF]
"This guidance is designed to assist practitioners in preventing child sexual exploitation (CSE), protecting children and young people who are at risk of abuse or are abused through sexual exploitation, and disrupting and prosecuting those who perpetrate
core
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang +7 more
wiley +1 more source
Updated trends in Child Maltreatment, 2012. [PDF]
National statistics from 2012 showed increases in some forms of child maltreatment for the first time in many years. While overall substantiated child maltreatment was flat from 2011 to 2012, there was a 2% rise in sexual abuse and a 5% rise in physical ...
Finkelhor, David +3 more
core +1 more source
PA accumulates after hypoxic‐ischemic injury and stabilizes the E3 ligase TRIM59 in OPCs. Stabilized TRIM59 enhances ubiquitination and degradation of Olig2, blocking differentiation and causing hypomyelination in PWMI. Modulating PA synthesis restores Olig2 levels, improves myelination, and ameliorates behavioral deficits, defining a metabolically ...
Xinyu Li +8 more
wiley +1 more source
Sexual abuse is defined as use of child or adolescent by the adults for satisfying of sexual urges and needs with forcing, threatening or tricking. Sexual abuse can be in the form of sexual abuse without touch, sexual touch, interfemoral intercourse ...
Evrim Aktepe
doaj
Which sexual abuse victims receive a forensic medical examination? : The impact of Children\u27s Advocacy Centers [PDF]
Objective This study examines the impact of Children\u27s Advocacy Centers (CAC) and other factors, such as the child\u27s age, alleged penetration, and injury on the use of forensic medical examinations as part of the response to reported child sexual ...
Cross, Theodore P +4 more
core +1 more source
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi +13 more
wiley +1 more source
Multifaceted Glance on Childhood Sexual Abuse and Incest [PDF]
An experience of domestic violence can lead to permanent physical, mental, and psychological harms, whether the child is a direct victim or a witness. Although having no standard definition, it is generally agreed that childhood sexual abuse and incest ...
Aslihan Okan Ibiloglu +3 more
doaj +1 more source
The Elimination of the Sexual Exploitation of Children: Two Policy Briefings [PDF]
The Oak Foundation child-abuse programme has funded and supported a range of civil society actors over the course of the last ten years, with the aim of reducing the incidence of the sexual exploitation of children, focusing primarily on work in East ...
core
Artificial Intelligence for Bone: Theory, Methods, and Applications
Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan +3 more
wiley +1 more source

