Results 131 to 140 of about 419,413 (333)

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

Clinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer, Ellen Cannady, Filip Cuyckens, Ulrike Glaenzel, Camille Granvil, Felix Huth, Alexander D. James, Wenying Li, Céline Veau, Graeme Young, Qin Yue, Gregory S. Walker, Upendra A. Argikar, Jonathan N. Bauman, Cathy Cantalloube, Yu‐Luan Chen, Ping Kang, Patricia Moliner, Mette L. Pedersen, Isabel Piel, Simone Schadt, Hanno Schieferstein, Julia Suchomel, Shuai Wang, S. Cyrus Khojasteh   +24 more
wiley   +1 more source

What is traumatic birth? A concept analysis and literature review [PDF]

, 2016
Background: A number of women experience childbirth as traumatic. This experience can have enduring and potentially lifelong effects on both mental and physical health, and have implications for the woman's relationship with her baby, partner and family.
Glover, Lesley, Greenfield, Mari, Jomeen, Julie   +2 more
core   +2 more sources

Women’s Perceptions of Living a Traumatic Childbirth Experience and Factors Related to a Birth Experience

International Journal of Environmental Research and Public Health, 2019
Although identified by the World Health Organization (WHO) as a global health priority, maternal mental health does not receive much attention even in the health systems of developed countries.
Julián Rodríguez-Almagro, A. Hernández-Martínez, David Rodríguez-Almagro, José Miguel Quirós-García, J. Martínez‐Galiano, J. Gómez‐Salgado   +5 more
semanticscholar   +1 more source

Optimal Dose and Safety of Intravenous Favipiravir in Hospitalized Patients With COVID‐19: A Dose‐Escalating, Randomized Controlled Phase Ib Study

Clinical Pharmacology &Therapeutics, EarlyView.
AGILE (NCT04746183) is a Phase Ib/IIa platform, evaluating candidates to treat COVID‐19. Candidate Specific Trial 6 evaluated the safety and optimal dose of a novel intravenous formulation of favipiravir in a dose‐escalating, open‐label, randomized, controlled, Bayesian adaptive Phase Ib trial.
Tim Rowland, Richard FitzGerald, Elizabeth Challenger, Laura Dickinson, Laura J. Else, Lauren Walker, Colin Hale, Victoria Shaw, Callum Kelly, Rebecca Lyon, Jennifer Gibney, Karim Dhamani, Margaret Irwin, Yvanne Enever, Michelle Tetlow, William Wood, Helen Reynolds, Justin Chiong, Orod Osanlou, Henry Pertinez, Katie Bullock, William Greenhalf, Andrew Owen, David G. Lalloo, Michael Jacobs, Julian A. Hiscox, Thomas Jaki, Pavel Mozgunov, Geoffrey Saunders, Gareth Griffiths, Saye H. Khoo, Thomas E. Fletcher, on behalf of the AGILE CST‐6 Study Group, Shazaad Ahmad, Christopher J. Edwards, Lesley Dry, Georgie McKenzie, Aleksandra Ros, Michael Stackpoole, Laura Bradley, Karen Jennings‐Wilding, Nicholas Paton, Fred Hayden, Janet Darbyshire, Amy Lucas, Ulrika Lorch, Andrew Freedman, Richard Knight, Steven Julious   +48 more
wiley   +1 more source

Normalisation of passivity during childbirth - positive experiences and trust in the healthcare system in serbia as generators of justifying passivity [PDF]

Temida
Research and practice show that within the healthcare system (HCS) in Serbia, women’s passivity during childbirth is normalised. Both HCS staff and female patients hold this representation of women as inherently passive.
Ninković Milica, Ilić Sandra, Damnjanović Kaja   +2 more
doaj   +1 more source

Support during birth interacts with prior trauma and birth intervention to predict postnatal post-traumatic stress symptoms [PDF]

, 2011
Background: Many women experience childbirth as traumatic and 2% develop post-traumatic stress disorder (PTSD). This study examined the role of health practitioner support and personal control during birth as predictors of PTS symptoms, adjusting for ...
Elizabeth Ford, Horowitz MJ, Koren D, Sauls D, Skari H, Susan Ayers, Wallston KA   +6 more
core   +1 more source

Social Comparison and Its Association With Disordered Eating Symptoms: A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk, Aysesu Bozdogan, Rachel Hughes, Phaedra Longhurst, Millie Chilvers, Ellen E. Fitzsimmons‐Craft   +5 more
wiley   +1 more source

Unexpected Consequences: Women’s experiences of a self-hypnosis intervention to help with pain relief during labour. [PDF]

, 2015
Background Self-hypnosis is becoming increasingly popular as a means of labour pain management. Previous studies have produced mixed results. There are very few data on women’s views and experiences of using hypnosis in this context.
A Werner, A Werner, A Werner, AM Cyna, AS Landolt, DAE Mairs, G Dick-Read, Helen Carr, Helen Spiby, HM Haines, J Attride-Stirling, J Svensson, JE Lally, K Guthrie, Kenneth Finlayson, KL Madden, L Andersson, L Jones, LE Mehl-Madrona, M Abbasi, M Stefanidou, ML Nolan, N Wainer, NK Lowe, P Hawe, Peter Whorwell, S Adams, S Garthus-Niegel, Soo Downe, Susan Hinder, V Nyman, WA Hall, YH Eng   +32 more
core   +2 more sources

Optimal approach to standardized documentation in epilepsy clinics: A scoping review

Epilepsia, EarlyView.
Abstract Clear documentation and transfer of information between health care providers is key to ensuring the delivery of high‐quality patient care. Our aim was to determine how to optimize and standardize physician documentation in outpatient epilepsy clinics as well as to highlight challenges and barriers to their implementation.
Shahab Marzoughi, Maren Kimura, Bamby Joseph, Alina Zhao, Diane L. Lorenzetti, Dang K. Nguyen, Mark Keezer, Colin B. Josephson, Nathalie Jetté   +8 more
wiley   +1 more source

Coping with Childbirth: Brain Structural Associations of Personal Growth Initiative

Frontiers in Psychology, 2017
Major life events require psychological adaptations and can be accompanied by brain structural and functional changes. The goal of the current study was to investigate the association of personal growth initiative (PGI) as a form of proactive coping ...
Judith Mangelsdorf, Judith Mangelsdorf
doaj   +1 more source