Psychosis-inducing effects of cannabis are related to both childhood abuse and COMT genotypes [PDF]
OBJECTIVE: To test whether the association between childhood abuse, cannabis use and psychotic experiences (PEs) was moderated by the COMT (catechol-O-methyltransferase) gene.
Alemany, Silvia +8 more
core +1 more source
Psychotic symptoms in young adults exposed to childhood trauma - A 20 year follow-up study [PDF]
Childhood adversity has been shown to increase the risk of psychotic symptoms in adult life. However, there are no previous studies looking at the association between experiencing a natural disaster during childhood and the development of psychotic ...
Alexander McFarlane +46 more
core +2 more sources
Cannabis use and hypomania in young people: a prospective analysis [PDF]
Background: Cannabis use in young people is common and associated with psychiatric disorders. However, the prospective link between cannabis use and bipolar disorder symptoms has rarely been investigated.
Bebbington, Paul +3 more
core +4 more sources
Childhood maltreatment and amygdala connectivity in methamphetamine dependence: a pilot study. [PDF]
IntroductionChildhood maltreatment, a well-known risk factor for the development of substance abuse disorders, is associated with functional and structural abnormalities in the adult brain, particularly in the limbic system.
Dean, Andy C +3 more
core +2 more sources
Neurofunctional Abnormalities during Sustained Attention in Severe Childhood Abuse. [PDF]
Childhood maltreatment is associated with adverse affective and cognitive consequences including impaired emotion processing, inhibition and attention.
Lena Lim +5 more
doaj +1 more source
Retrospective Reports of Childhood Trauma in Adults with ADHD [PDF]
Although studies have documented higher prevalence of abuse in children with ADHD, no studies have investigated childhood reports of abuse in individuals identified withADHDin adulthood.
Brown, D.L. +3 more
core +1 more source
Childhood abuse in the etiological continuum underlying psychosis from first-episode psychosis to psychotic experiences [PDF]
Goal The present study aimed to examine the prevalence of child abuse across the continuum of psychosis. Patients and methods The sample consisted of 198 individuals divided in three groups: (1) 48 FEP patients, (2) 77 individuals scoring high ...
Alemany, Silvia +7 more
core +2 more sources
Impact of Childhood Abuse on the Risk of Non-Suicidal Self-Injury in Mainland Chinese Adolescents. [PDF]
Childhood abuse has been associated with significant increases in non-suicidal self-injury (NSSI) behaviors in adolescents; however, only general definitions of this risk indicator have been examined.
Yuhui Wan +3 more
doaj +1 more source
Association between childhood adversities and long-term suicidality among South Africans from the results of the South African Stress and Health study: a cross-sectional study [PDF]
Objective: Suicide and suicidal behaviours are significant public health problems and a leading cause of death worldwide and in South Africa. We examined the association between childhood adversities and suicidal behaviour over the life course.
Bishop, Melanie +5 more
core +2 more sources
Background: It is increasingly becoming accepted that substance use disorders, including substance abuse and substance dependence, are closely related to childhood trauma and posttraumatic stress disorders.
Annett Lotzin +8 more
doaj +1 more source

