Results 121 to 130 of about 138,344 (267)

Blood culture: specificity in childhood bacterial pneumonia

Revista do Instituto de Medicina Tropical de São Paulo, 1995
Bernardo Ejzenberg, Joaquim C. Rodrigues, Vera S. Dias Vieira, Maria C. C. Brandileone, Evandro Roberto Baldacci, Yassuhiko Okay   +5 more
doaj   +1 more source

Using the Socio-Ecological Model to Explore Parents' Resilience and Perceptions of Adverse Childhood Experiences: A Qualitative Study in the Southeastern United States. [PDF]

Healthcare (Basel)
Dominguez MG, Markham C, Springer AE, Brown LD.   +3 more
europepmc   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

Advanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang, Yimin Gong, Jianing Li, Tianze Wu, Mingli Deng, Yannan Yang   +5 more
wiley   +1 more source

Voluntary self-reclusion (Hikikomori) across cultures: A conceptual viewpoint. [PDF]

Indian J Psychiatry
Biswas T, Mohapatra D, Panigrahi S.
europepmc   +1 more source

Therapeutic Gene Editing of APOE4 in Sporadic Alzheimer's Disease via Prime Editor 7

Advanced Science, EarlyView.
Prime Editor 7‐mediated conversion of APOE4 to APOE3 alleviates Alzheimer's disease‐associated pathology in AD mouse models and patient‐derived neurons and improves cognitive performance in vivo, supporting therapeutic genome editing as a promising strategy for APOE4‐associated neurodegeneration.
Yunkyung Kim, Gaeun Lee, Saemin An, Hanseul Park, Hongwon Kim, Jisung Kim, Soi Kang, Sumin Kim, Daeyeol Kwon, Jeonghyun Park, Yerim Hwang, Seonghun Kim, Xiuwen Yuan, Jaehoon Jeong, Hamin Lee, Hui Kwon Kim, Jongpil Kim   +16 more
wiley   +1 more source

Help-Seeking Behavior of Adults with Adverse Childhood Experiences in Rural China. [PDF]

Behav Sci (Basel)
Chen W, Zhang Y, Chen J.
europepmc   +1 more source

G‐Quadruplexes: Structural Diversity and Emerging Roles in Biomolecular Condensation

Advanced Science, EarlyView.
G‐quadruplexes (G4s) fold into diverse intra‐ and intermolecular structures, positioning them as emerging regulators of biomolecular condensation. Mechanistically, G4s autonomously form condensates, act as structural platforms to initiate and stimulate condensation, or induce phase transitions.
Wenmeng Wang, Qingqing Xu, Yuxin Zhang, Fang Liu, Guangchao Sui, Dangdang Li   +5 more
wiley   +1 more source

Meningeal-tumor interactions define distinct modes of leptomeningeal colonization in Group 3 medulloblastoma. [PDF]

Acta Neuropathol Commun
Jimenez Garcia L, Ryan LN, Gross AC, Albrecht AM, Walters JH, Leonard JR, Roberts RD, Reinecke JB.   +7 more
europepmc   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

The <u>W</u>heezing, <u>A</u>sthma and <u>V</u>iral effects on the <u>E</u>pithelial <u>S</u>tructure and function (WAVES) birth cohort study: rationale, design and methods to understand airway development and the role of early-life respiratory viral infections on childhood asthma inception. [PDF]

BMJ Open Respir Res
Hartert T, Rosas-Salazar C, Newcomb DC, Snyder BM, Berdnikovs S, McKennan C, Osmundson S, Liu Z, Tafoya E, Folad W, Simon P, Reiss S, Poleon K, Cephus JY, Kuehnle SN, McKernan KE, Ma S, Anderson LJ, Gebretsadik T.   +18 more
europepmc   +1 more source