Results 41 to 50 of about 13,246 (176)

A case report of late presentation of asymptomatic primary congenital glaucoma

TNOA Journal of Ophthalmic Science and Research, 2020
An asymptomatic 3-year-old child presented with megalocornea, mild corneal haze, high intraocular pressure, and advanced optic disc damage in both eyes. The child was taken up for trabeculectomy and trabeculotomy in the right eye and trabeculectomy alone
Raja Vidya, Srilekha Pallamparthy, Rupa Anjanamoorthy, Rajendrababu Sharmila   +3 more
doaj   +1 more source

Nudix hydrolase 15 deficiency and azathioprine toxicity in a liver transplant recipient: A case report

JPGN Reports, EarlyView.
Abstract Thiopurines, such as azathioprine (AZA), are among the immunosuppressants used to prevent allograft rejection. Thiopurines are metabolized by thiopurine S‐methyltransferase (TPMT) and nudix hydrolase 15 (NUDT15) enzymes, and their functions are highly influenced by genetic variation. We present a 6‐year‐old female with recurrent acute cellular
Jenny Q. Nguyen, Natalie Rodriguez, Kimberly A. Chapman, Matthew A. Deardorff, Keith Z. Hazleton   +4 more
wiley   +1 more source

Clinical Classification of Childhood Glaucomas [PDF]

Archives of Ophthalmology, 2010
An updated classification of the primary and secondary childhood glaucomas is offered for clinical use, and associated systemic diseases are included to enable their early recognition in children with known glaucoma.Approximately 650 clinical records of patients with pediatric glaucoma were reviewed for type of glaucoma and associated systemic disease.
Helen H, Yeung, David S, Walton
openaire   +2 more sources

Advancing Artificial Intelligence in Myopia Management: From Predicting Progression to Supporting Clinical Decisions

Med Research, EarlyView.
The AI‐enabled multimodal framework for whole‐life myopia management. Graphical abstract illustrates the transition of myopia care from premyopia to myopia, high myopia, and pathologic myopia. Multimodal data, including demographic and refractive information, genetic, behavioral and environmental factors, ophthalmic imaging, and omics profiles, can be ...
Zewei Zhang, Yun Wang, Lifei Zhang, Dongmei Chen, Weijie Zhang, Fang Li, Jibo Zhou   +6 more
wiley   +1 more source

Unilateral buphthalmos in a patient with short stature: a rare case of dual recessive disorders [PDF]

Revista Brasileira de Oftalmologia
Bupthalmos is characterized by congenital enlargement of the eyeball due to uncontrolled glaucoma in early childhood, which is mostly caused by primary congenital glaucoma.
Juan Clinton Llerena Júnior, Maria Eduarda Gomes, Tatiana Sa Pacheco Carneiro Magalhaes, Natana Chaves Rabelo, Sayonara Maria de Carvalho Gonzalez   +4 more
doaj   +2 more sources

Ultrasound biomicroscopy: An invaluable asset in glaucoma

Kerala Journal of Ophthalmology, 2023
Ultrasound biomicroscopy (UBM) is a non-invasive and high-resolution approach to studying anatomical characteristics and relationships among various anterior segment components.
Sagarika Snehi, Ashok Kumar Singh, Sushmita Kaushik   +2 more
doaj   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Retinal neurovascular alterations are associated with optic radiation microstructure in adrenomyeloneuropathy: A susceptibility separation MRI study

VIEW, EarlyView.
In a cross‐sectional cohort of 104 participants, 7 T susceptibility separation MRI and diffusion imaging were combined with retinal imaging and visual evoked potentials to characterize visual pathway involvement in adrenomyeloneuropathy (AMN). Absolute diamagnetic susceptibility, a myelin‐associated measure, and fractional anisotropy (FA) showed ...
Ronghao Li, Jun Li, Chongyi Li, Xingang Wang, Wenyu Zhou, Yangcheng Zou, Zhiming Zhen, Li Xiao, Na Liang, Zongxing Zou, Junru Yang, Hui Yang, Chunhua Fu, Weiqi Chen, Yuyu Chen, Chen Liu, Hongjiang Wei, Liang Tan   +17 more
wiley   +1 more source

Optimal Resources for Children's Surgery 2: Tiered Recommendations for Minimum Essential Children's Surgical Procedures Across Health System Levels

World Journal of Surgery, EarlyView.
In 2015 the World Health Assembly (WHO), based on recommendations by the Lancet Commission on Global Surgery, passed resolution (68:15) on strengthening emergency and essential surgical care and anesthesia as a component of universal health coverage. However, children's surgery was not adequately represented and in response, the Global Initiative for ...
Arpita Biswangree, Emmanuel A. Ameh, Kokila Lakhoo, Mohamed Shalaby, Sarah Beth Cairo, on behalf of GICS Membership, Abdelhafeez Hafeez, Dayang A Abdul Aziz, Abdur‐Rahman Lukman Olajide, Simone Abib, Mohammed J. Aboud, Abu Bakr Abdullah Adam Amal, Maimuna Abubakar, Piero Ali Alberti, Abdelbasit Elsayed, Abdullah Mohd Yusof, Abellar Hilda, Acharya Utsav, Amaraegbulam Peace Ifeoma, Amde Samuel Negash, Antoine Seraphin Gbenou, Arca Marjorie, Axt Jason, Banu Tahmina, Bezuhly Michael, Biswangree Arpita, Marilyn W. Butler, Michael Buzuhly, Sarah B. Cairo, Juan Francisco Campos Rodezno, Maija Cheung, Chirdan Lohfa, Milind Chitnis, Zachary Clapp, Hannah Cockrell, Aline Coltro, Deshpande Gaurav, Diao Mei, Donou Amivi Alice, Beda Espineda, Faye M. Evans, Ewnte Biniam, Fadhili Bake Jacques, Faktor Kara, Farmer Diana Lee, Gaffar Ilijana, Ganey Michael, Gathuya Zipporah, J. F. Gonzalez‐Zamora, Christa N. Grant, Gray Rebecca Crane, Hasnaien Ahmed, Hettiarachchi Mathula, Hsu Phillip, Ibrahim Rahma Wala Mohammed, Romeo C. Ignacio, Inglin Sophie, Islam Saleem, Kageni Maina Reuel, Kengo Nathan Ezie, Kisa Phyllis, Lakhoo Kokila, Langer Monica, Leodoro Basil, Lindert Judith, Lobos Pablo Andrés, Løfberg Katrine, Madhuri Vrisha, Martin Yturralde Erick, Mazingi Dennis, Mcleod Elizabeth Jane, John G. Meara, Felicity Vidya Mehendale, Felicity Vidya Mehendale, Milano Leecarlo, Hanifah N. A. Mohd, Moreno Amabelle, Mpongo Yves, Mrutu Salehe, Muthumani Abirami, Nah Shireen Anne, Naik‐Mathuria Bindi, Nandi Biplab, Ramesh M. Nataraja, Newton Odongo Charles, Nimanya Stella Alice, Nixon Cathrine, Ntegerejuwampaye Angélique, Obi Nkeiruka, Obisesan Aderonke Omoyeni, Odera Agneta, Ondima Lucienne Irene Patricia, Maryrose O. Osazuma, Owusu Ofori Emmanuel, Ozgediz Doruk, Pacheco Cesar Hector Alberto, Patel Nirav, Peer Shazia, Phelps Janey, Pilkington Mercedes, Poenaru Dan, Ravindran Vinitha, Rolle Udo, Saldaña Gallo Lily, Saleh Abdullah, Samad Lubna, Sedano Sabrina, Sethi Bijaya Kumar, Justina Seyi‐Olajide, Shalaby Mohamed Sameh, Sharma Mehek, Siddiqui Sabina, Stephens Caroline, Stoltz Judith, Talat Nabila, Warwick J. Teague, Tekant Gonca, Tumba Kapaso Nadyn, Wildhaber Barbara, Ava C. Yap, Zanon Nelci, Zope Madhushree   +121 more
wiley   +1 more source