Results 51 to 60 of about 1,752,397 (306)

Childhood obesity and the associated rise in cardiometabolic complications

open access: yesNature Metabolism, 2020
Childhood obesity is one of the most serious global public-health challenges of the twenty-first century. Over the past four decades, the number of children and adolescents with obesity has risen more than tenfold.
S. Caprio, N. Santoro, R. Weiss
semanticscholar   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The association between gestational diabetes mellitus and Dietary Diabetes Risk Reduction Score: a case-control study

open access: yesBMC Endocrine Disorders
Background Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication influenced by dietary patterns. The Dietary Diabetes Risk Reduction Score (DDRRS), a composite index evaluating diet quality in relation to diabetes risk, may be a ...
Fatemeh Maleki Sedgi   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Association of childhood obesity with risk of early all-cause and cause-specific mortality: A Swedish prospective cohort study

open access: yesPLoS Medicine, 2020
Background Pediatric obesity is associated with increased risk of premature death from middle age onward, but whether the risk is already increased in young adulthood is unclear. The aim was to investigate whether individuals who had obesity in childhood
Louise Lindberg   +4 more
semanticscholar   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Association between oxidative balance score and gestational diabetes mellitus risk: a case-control study

open access: yesBMC Endocrine Disorders
Background Gestational diabetes mellitus (GDM) is a common pregnancy complication closely associated with increased oxidative stress. The Oxidative Balance Score (OBS) integrates dietary and lifestyle factors influencing oxidative stress, yet its ...
Fatemeh Maleki Sedgi   +5 more
doaj   +1 more source

Process evaluations of early childhood obesity prevention interventions delivered via telephone or text messages: a systematic review

open access: yesInternational Journal of Behavioral Nutrition and Physical Activity, 2021
Background Increasingly, public health interventions are delivered via telephone and/or text messages. Recent systematic reviews of early childhood obesity prevention interventions have not adequately reported on the way interventions are delivered and ...
Mahalakshmi Ekambareshwar   +7 more
doaj   +1 more source

Clinical and Modifiable Factors Associated With Disability and Relapse in MOGAD: A Multicentre Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Factors associated with relapse course and disability in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD) remain incompletely understood. Objectives To identify clinical and modifiable factors associated with relapse and disability in MOGAD. Methods In this ambispective multicentre cohort study using data from
Yingtao Wang   +23 more
wiley   +1 more source

Association of household food insecurity with sociodemographic factors and obesity in US youth: findings from the National Health and Nutrition Examination Survey 2017–2018

open access: yesFrontiers in Public Health
BackgroundThe objective is to determine the prevalence of household food insecurity (HFI) based on sociodemographic factors and their relationship to obesity in youth.MethodsThe study included a sample of 1,962 youth (aged 6–18) from the National Health ...
Amin Mokari-Yamchi   +4 more
doaj   +1 more source

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