Results 111 to 120 of about 1,305,310 (255)

childhood emotional trauma resulting in limiting beliefs, toxic relationships and the devastating effects on psychiatric patients.

, 2023
the following results of childhood emotional trauma : limiting beliefs, poor self concept, disconnection from the present moment have the capacity to perpetuate psychopathology and psychiatric illnesses, making them worse or acting as a continuous ...
onyeachu, ngozi diepriye peace
core  

The relationship between childhood trauma and cyberbullying: a meta-analysis of mainland Chinese adolescents and young adults

Humanities & Social Sciences Communications
In recent years, scholars have extensively investigated the correlation between childhood trauma and cyberbullying. However, findings in this area have been inconsistent.
Shunyu Li, Kelare Ainiwaer, Yuxuan Zhang
doaj   +1 more source

The relationship between childhood trauma and romantic relationship satisfaction: the role of attachment and social support

Frontiers in Psychiatry
ObjectiveTo investigate the impact of childhood trauma on romantic relationship satisfaction among college students, focusing on the mediating role of attachment and the moderating role of social support.MethodsA total of 1,404 college students from Wuhu,
Lijuan Quan, Kun Zhang, Haiyan Chen
doaj   +1 more source

Early Retinal UCHL1 Dysregulation Coupled With Synaptic Loss Reflects Alzheimer's Disease Severity

Advanced Science, EarlyView.
This study identifies synapse‐enriched deubiquitinase UCHL1 as an early Aβ‐responsive regulator of retinal synaptopathy in Alzheimer's disease. Retinal UCHL1 loss accompanies excitatory synapse degeneration, p75NTR activation, and neuroinflammation, and predicts Braak stage and cognitive decline. Aβ42 fibrils trigger synaptic and UCHL1 depletion before
Altan Rentsendorj, Jean‐Philippe Vit, Alexandre Hutton, Yosef Koronyo, Saba Shahin, Edward Robinson, Ernesto Barron, Anthony Rodriguez, Ousman Jallow, Julia Sheyn, Bhakta Prasad Gaire, Lalita Subedi, Miyah R. Davis, Barathan Gnanabharathi, Alexander V. Ljubimov, Stuart L. Graham, Vivek K. Gupta, Mehdi Mirzaei, Debra Hawes, Katlin Silm, Keith L. Black, Lon S. Schneider, Alfredo A. Sadun, Jesse G. Meyer, Dieu‐Trang Fuchs, Maya Koronyo‐Hamaoui   +25 more
wiley   +1 more source

Organoid Brain‐Machine‐Interface Devices for Central Nervous System Repair

Advanced Science, EarlyView.
We envision organoid brain‐machine‐interface (Organoid‐BMI) devices as new biohybrid bidirectional communication pathways to connect the human CNS and the external world for personalized CNS repair and regeneration. ABSTRACT Central nervous system (CNS) repair and regeneration suffer from tremendous clinical challenges due to current limitations in ...
Yantao Xing, Yang Yang, Zichen Hong, Chunhui Tian, Huiyu Chu, Susanne Clara Prokop, Hongwei Cai, Mingxia Gu, Jason Tchieu, Ken Mackie, Feng Guo   +10 more
wiley   +1 more source

Mediating Role of Self-Compassion and Psychological Resilience in the Relationship between Childhood Trauma and Psychosomatic Symptoms in a Non-Clinical Adult Sample

Psikiyatride Güncel Yaklaşımlar
Objective: This study investigates the mediating effects of self-compassion and psychological resilience on the association between childhood trauma and psychosomatic symptoms in a non-clinical adult population.
Kahraman Güler, Simay Ahi
doaj   +1 more source

Soft, Multi‐Wavelength Photoplethysmography Enables Reliable Neonatal Blood Pressure Monitoring Via Error Stratification

Advanced Science, EarlyView.
A soft hybrid multi‐wavelength PPG wearable acquires neonatal signals. Synchronized PPG and invasive ABP data are segmented into fixed windows. A 1D‐EfficientNet model predicts segment‐level SBP and DBP. Model performance is examined with retrospective subgroup analysis across acquisition conditions.
Wenqi Shi, Lanlan Mi, Jiarong Chen, Biao Liu, Min Wang, Zisheng Dai, Bin Liu, Ruize Gao, Yunfeng Lin, Weiwei Guo, Guoxing Wang, Wenyi Luo, Cheng Chen   +12 more
wiley   +1 more source

A Blood‐Derived Factor Rescues ALS: Platelet Factor 4 Activates OPTN‐Dependent Autophagy to Clear SOD1 Aggregates Independently of PINK1

Advanced Science, EarlyView.
Systemic platelet factor 4 (PF4) is significantly depleted in amyotrophic lateral sclerosis (ALS). Peripheral PF4 replenishment restores central proteostasis by driving OPTN‐dependent, PINK1‐independent selective autophagy in motor neurons. This intervention effectively clears toxic SOD1 aggregates, blunts glial activation, and preserves neuromuscular ...
Qingjian Xie, Yanbo Zhu, Wenhua Jiang, Haobo Xie, Yaojia Li, Mengjie Hu, Kezheng Li, Huan Yu, Yixuan Pan, Chaoyi Jiang, Xueqin Song, Dongsheng Fan, Binbin Deng   +12 more
wiley   +1 more source

Association between childhood trauma and anxiety among first-year MBBS students at MGM Medical College and Hospital, Chhatrapati Sambhajinagar, Maharashtra, India: a cross-sectional study

MGM Journal of Medical Sciences
Background: Childhood trauma is a well-known risk factor for developing anxiety disorders during adolescence and early adulthood, with lasting effects on emotional regulation and stress response systems.
Shraddha Jadhav, Mangesh Kadam
doaj   +1 more source

Impact of childhood trauma on cognitive function in patients with bipolar disorder

Frontiers in Psychiatry
BackgroundPatients with bipolar disorder (BD) frequently exhibit cognitive impairments. However, the association between childhood trauma as a risk factor for BD and cognitive deficits remains ambiguous.ObjectiveTo investigate the relationship between ...
Zhiyang Zhang, Zhiyang Zhang, Chenyu Zhou, Chenyu Zhou, Zhen Mao, Zhen Mao, Yue Sun, Yue Sun, Lei Zhao, Lei Zhao, Tian Li, Tian Li, Chuanyue Wang, Chuanyue Wang, Qijing Bo, Qijing Bo   +15 more
doaj   +1 more source