Results 101 to 110 of about 9,619 (261)

PECULIARITIES OF EXERCISING THE RIGHTS AND INTЕRESTS OF СHILDREN IN THE REPUBLIC OF KАZAKHSTAN IN THE FRAMEWORK OF THE COMPARATIVE ANALYSIS OF THE INTERNATIONAL STАNDARDS

Хабаршы. Заң сериясы
This article studied the specificity of the legal system on the protection of children`s rights functioning in the Republic of Kazakhstan, attention is paid to the basic principles of international cooperation on problems of children.
К.Т. Жуманова, Ш.У. Ярилхапова, А.О. Ергебекова, А.Б. Тойжанова, М.Б. Биболаева   +4 more
doaj  

Absence seizures: Update on signaling mechanisms and networks

Epilepsia Open, EarlyView.
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley   +1 more source

A systemic type of juvenile idiopathic (rheumatoid) arthritis in children and adolescents: new in the treatment (review of literature and own observations)

Zdorovʹe Rebenka, 2017
The main views on one of the most complex pathological conditions in pediatric rheumatology, namely systemic arthritis, are presented. The characteristics of the classification positions of this disease are given, the pathogenetic bases, topical at the present time, the main approaches to its therapy are covered.
L.F. Bogmat, N.S. Shevchenko
openaire   +1 more source

Sialidosis type I: How to alleviate disabling myoclonic seizures?—A multicenter analysis of eight cases and review of the literature

Epilepsia Open, EarlyView.
Abstract Objective Sialidosis type I (ST‐1) is an autosomal‐recessive, very rare, progressive lysosomal storage disorder caused by pathogenic variants in NEU1. It is clinically characterized by progressive ataxia, myoclonic seizures (MS), bilateral tonic–clonic seizures (BTCS), and distinctive ophthalmological findings.
Janina Gburek‐Augustat, I‐Chun Lee, Marica Rubino, Vehap Topçu, Melissa Chavez‐Castillo, Shao Ching Tu, Marwan Shinawi, Isabel Alfradique‐Dunham, Manouela Valtcheva, Astrid Adarmes‐Gómez, Daniel Macias‐Garcia, Laura Laura Muñoz‐Delgado, Silvia Jesús, Pablo Mir, Andreas Merkenschlager, Antonietta Coppola   +15 more
wiley   +1 more source

The causal relationship between systemic lupus erythematosus and juvenile myoclonic epilepsy: A Mendelian randomization study and mediation analysis

Ibrain, Volume 11, Issue 1, Page 98-105, Spring 2025.
Mendelian randomization (MR) studies were conducted using the inverse‐variance weighted (IVW) method, MR‐Egger and weighted median on juvenile myoclonic epilepsy (JME), and systemic lupus erythematosus (SLE) data from the Integrative Epidemiology Unit (IEU) Open genome‐wide association study (GWAS) database and the International League Against Epilepsy
Sirui Chen, Ningning Zhang, Ruirui Zhang, Lan Zhang, Dadong Luo, Junqiang Li, Yaqing Liu, Yunan Wang, Xinyue Duan, Xin Tian, Tiancheng Wang   +10 more
wiley   +1 more source

Complement C3 mediates adolescent social isolation‐induced hippocampal synaptic deficits and sex‐specific emotional dysfunction

Interdisciplinary Medicine, EarlyView.
Adolescent social isolation disrupts hippocampal function and exacerbates emotional symptoms, with sex‐specific patterns, as shown by human studies. In mice, social isolation decreased hippocampal synaptic density and calcium signaling, upregulated complement proteins, and activated complement‐mediated microglial synaptic phagocytosis.
Yuwan Qi, Siying Weng, Qiao Yin, Mengqi Li, Liang Shen, Enyou Qiao, Lu Gao, Yihan Wang, Yuxuan Li, Weifeng Luo, Qilin Zhang, Jing Wang, Jianfeng Feng, Qifei Cong   +13 more
wiley   +1 more source

Clinical and genetic analysis and literature review of children with myotonia congenita due to CLCN1 mutations

Italian Journal of Pediatrics
Background Myotonia congenita (MC) is mainly caused by variants in the CLCN1 Gene, which is characterized by having difficulty in relaxing the muscle after active contraction, known as myotonia. This study aims to investigate the clinical characteristics
Xin Wang, Shangyu Wang, Hongdan Qi, Bing Wu, Mingying He, Gang Zhang   +5 more
doaj   +1 more source

Los modelos familiares en la Literatura Infantil y Juvenil: un catálogo para Educación Infantil / Family models in Children's and Young Adult Literature: a catalogue for Early Childhood Education

TEJUELO. Didáctica de la Lengua y la Literatura. Educación
The study highlights family diversity in society, where different models can be considered: two-parent, homoparental, single-parent, reconstituted, foster, adoptive, extended and intercultural and transnational. In this context, Children's and Young Adult Literature can become a resource that provides students with examples, stories and references that
Paula Moreno Losa, María Isabel De Vicente-Yagüe Jara   +1 more
openaire   +1 more source

Evaluating Youth Participatory Action Research in the Americas: Comparative Insights on Empowerment, Methodologies, and Social Change

Journal of Adolescence, EarlyView.
ABSTRACT Introduction Youth Participatory Action Research (YPAR) positions adolescents as co‐researchers to investigate and address social issues affecting their lives. While YPAR has gained global prominence, comparative research examining how it is conceptualized and practiced across regional contexts remains limited.
John Diaz, Paola Velasquez Quintero, Cody Gusto, Ivan Muñoz‐Echeverri, Camilo Norena Herrera, Laura Valencia   +5 more
wiley   +1 more source

Yes, Friendship and Love Can Be Bought and Sold

Journal of Applied Philosophy, EarlyView.
ABSTRACT Can friendship and love be bought and sold? I argue yes, contrary to philosophical consensus. The prevailing view rests on the common error of over‐reliance on idealized conceptions of friendship and love that bear little resemblance to actual relationships.
Simone Sommer Degn
wiley   +1 more source