Results 61 to 70 of about 9,619 (261)

Methodological approaches to the use of the Register of children with juvenile arthritis at the level of specialized medical care

open access: yesНаучно-практическая ревматология, 2019
Juvenile arthritis (JA) is a disease of unknown etiology that begins before the age of 16 years and lasts for at least 6 weeks. The main objective of most existing international registers of children with JA is assessment various aspects of the efficacy ...
V. A. Malievsky   +8 more
doaj   +1 more source

Integrating whole‐bone and regional analyses to understand human scapular growth

open access: yesThe Anatomical Record, EarlyView.
Abstract This study investigates ontogenetic changes in human scapular morphology using three‐dimensional geometric morphometrics with whole‐bone and region‐specific analyses. The aim is to evaluate whether the scapula follows a regular developmental pattern and whether its functionally distinct components, the scapular spine (SS) and glenoid fossa ...
Azahara Salazar‐Fernández   +3 more
wiley   +1 more source

Pelvic morphology and body size in relation to the preauricular sulcus: Evidence from medieval to modern Iberia

open access: yesThe Anatomical Record, EarlyView.
Abstract The preauricular sulcus has long been debated as a pelvic feature variably attributed to obstetric stress, ligamentous traction, and broader biomechanical processes. To clarify its determinants, we analyzed 409 adult individuals from three archeological and one early modern skeletal collection from the Iberian Peninsula, integrating graded ...
Rebeca García‐González   +5 more
wiley   +1 more source

A literatura juvenil brasileira no início do século XXI: autores, obras e tendências

open access: yesEstudos de Literatura Brasileira Contemporânea, 2010
The present research offers a study on Brazilian youth literature published in the first decade of this century, by analyzing the books awarded by National Foundation of Children’s and Youth Books, and Brazilian Book Chamber, which awards the prize ...
Gabriela Luft
doaj  

Treatment of a Large Cohort of Childhood Chronic Noninfectious Uveitis in a Multicentric Large Study: Adalimumab Versus Methotrexate as First‐Line Therapy

open access: yesArthritis &Rheumatology, EarlyView.
Objective Treatment of childhood chronic idiopathic uveitis (cCIU) is predominantly based on studies in juvenile idiopathic arthritis–associated uveitis and expert opinion. Our aim was to report the treatment outcomes of our cohort of cCIU. Methods Retrospective multicenter study involving the rheumatology and ophthalmology units at Florence, Italy ...
Ilaria Maccora   +5 more
wiley   +1 more source

Inosine‐Triphosphate‐Pyrophosphatase Activity as a Potential Predictor of Methotrexate Remission in Juvenile Idiopathic Arthritis

open access: yesArthritis &Rheumatology, EarlyView.
Objective Methotrexate (MTX) is the first‐line therapy for juvenile idiopathic arthritis (JIA), but up to 40% of patients do not respond to it. Low inosine triphosphate pyrophosphatase (ITPA) activity has been associated with reduced clinical remission. We investigated the role and underlying mechanisms of ITPA in vitro. Methods ITPA enzymatic activity
Sofia Sindici Forgiarini   +19 more
wiley   +1 more source

RESOCIALIZATION OF ADOLESCENTS ON PROBATION: PSYCHOSOCIAL APPROACH WITH ELEMENTS OF COACHING [PDF]

open access: yesAlfred Nobel University Journal of Pedagogy and Psychology
The article discusses current approaches to the resocialization of adolescents on probation in the con- text of psychosocial support. The purpose of the article is to identify the specific features of the resocialisation of conditionally sen- tenced ...
Inesa Harkusha, Serhii Dubinskyi
doaj   +1 more source

A multifaceted interplay between hemophagocytosis, IL‐18 and type I IFN distinguishes Still disease from other autoinflammatory diseases

open access: yesArthritis &Rheumatology, Accepted Article.
Objectives The unknown pathophysiology and the lack of specific features for systemic Juvenile Idiopathic arthritis and adult‐onset Still disease (collectively Still disease/SD) delays diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory diseases ...
Yvonne M. Mueller   +17 more
wiley   +1 more source

Tofacitinib treatment of systemic juvenile idiopathic arthritis: a case report and literature review

open access: yesFrontiers in Pediatrics
ObjectiveSystemic juvenile idiopathic arthritis (sJIA), a particularly aggressive form of childhood arthritis, is characterized by persistent systemic inflammation.
Meifang Zhu   +6 more
doaj   +1 more source

Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder

open access: yesAutism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing.
Kyle M. Roddick   +3 more
wiley   +1 more source

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