Results 111 to 120 of about 8,464,968 (354)

Suppressing t(4;11) Acute Leukemia by Lipopolymer Nanoparticle Delivery of siRNA Targeting KMT2A::AFF1 with Enhanced Extrahepatic Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
This study introduces a new lipopolymer nanoparticle (LPNP) system that efficiently delivers siRNA to leukemia cells. The LPNPs silence the leukemia fusion gene KMT2A::AFF1, induce apoptosis, and decrease leukemia burden in mice. These results demonstrate the potential of LPNPs as a targeted siRNA therapy for acute lymphoblastic leukemia.
Mohammad Nasrullah   +9 more
wiley   +1 more source

A Comprehensive Review of Clinical Studies on Bacterial Cellulose: From the Earliest Uses to Contemporary Innovations

open access: yesAdvanced Healthcare Materials, EarlyView.
Bacterial cellulose has undergone a transformative journey from early applications to its role in advanced regenerative medicine. The review has a pedagogical ambition, offering clear pathways for future research and clinical adoption. Harmonizing regulatory standards and conducting larger, well‐designed clinical trials with standardized endpoints will
Thomas Meslier   +3 more
wiley   +1 more source

Literatura infantil contemporânea: o passado (revestido) bate à porta

open access: yesEstudos de Literatura Brasileira Contemporânea, 2010
Contemporary children's literature has revealed a tendency to upgrade speeches of the past by means of creating scenarios, which show conflicts situated within a distant time from the contemporary reader.
Flávia Brocchetto Ramos   +1 more
doaj  

Rediscovering a Child's Sense of Wonder: Depictions of Nature and Outdoor Play in Historical Children's Literature

open access: yesChildren and Libraries, 2014
■ ■ Did these depictions relate to or reflect movements promoting the health and welfare of children? For example, I am particularly interested in the “fresh air” and playground movements of the Progressive era and how they compare and contrast to similar efforts today, such as those inspired by the work of Richard Louv, author of Last Child in the ...
openaire   +2 more sources

Antitumoral Efficacy of AuNRs‐Laden ECFCs In Vitro and In Vivo: Decoding the Heat and Rays Combo Treatment in Breast Cancer and Melanoma Cells

open access: yesAdvanced Healthcare Materials, EarlyView.
Endothelial Colony Forming Cells (ECFCs) acted as cellular cyborgs, stealthily transporting gold nanorods (AuNRs) into tumors to enable targeted near‐infrared (NIR) hyperthermia combined with radiotherapy. This approach triggers ferroptosis in melanoma and inhibits autophagy in breast cancer, revealing a tumor‐specific response to nanomaterial‐assisted
Cecilia Anceschi   +26 more
wiley   +1 more source

Bilirubin Sensing Using Organic Electrochemical Transistors: Role of Gate Materials and Operational Parameters

open access: yesAdvanced Healthcare Materials, EarlyView.
This study explores PEDOT:PSS‐based OECTs as sensitive bilirubin sensors, revealing that polarizable gate electrodes (Au, Pt, glassy carbon) enable detection while non‐polarizable Ag/AgCl gates suppress response. Operational parameters modulate current direction, suggesting complex interfacial dynamics.
Yunjia Song, Sihui Xu, Onur Parlak
wiley   +1 more source

THE USE OF CHILDREN’S LITERATURE IN SOCIAL STUDIES: A COMPARATIVE STUDY IN THE USA AND TURKEY

open access: yesSakarya Üniversitesi Eğitim Fakültesi Dergisi, 2013
In this study the importance of giving place to children’s literature in Social Studies in the USA and Turkey has been described upon briefly. It has been observed that social studies instruction fields in the USA have highly affluent studies in regard ...
Ahmet Şimşek
doaj  

Do we listen to what makes children happy? A systematic literature review of voices of children aged 3–7 years in educational research

open access: yesJournal of Happiness and Health
Research shows that children’s views and experiences are usually overlooked in discussions related to their own happiness and wellbeing. In fact, the largest international study to date on children’s wellbeing only included children aged 8-12.
Angel Urbina-Garcia
doaj   +1 more source

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