Results 61 to 70 of about 7,028,389 (249)

Critical Plant Studies and Children’s Literature

open access: yes, 2017
ISBN for host publication: 9781474414630 ...
Kokkola, Lydia, Kokkola, Lydia,
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Delights of Dinners, Pleasures of Picnics in the “Make-believe” Food Fantasies of the Edwardian Children’s Literature Translated into Polish

open access: yes
This chapter was written as a part of the OPUS 21 grant of the National Science Centre, Poland, project no. 2021/41/B/HS2/00876: Half a Century of Children’s Literature in Poland. Texts for a Young Audience in the Context of Cultural Production and Power:
Wieczorkiewicz, Aleksandra
core   +1 more source

Greater understanding of spacing needs for children’s eye movements during on-screen reading is required [PDF]

open access: yes, 2009
This paper endeavors to consolidate current knowledge and empirical research concerning the use of typography for children’s on-screen reading. This paper is not intended as a full literature review, but attempts to raise awareness of the areas required ...
Vanderschantz, Nicholas
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Litteratur för integration av arbetarbarn

open access: yesTidskrift för Litteraturvetenskap, 2011
Tales for the Integration of Working-Class Children: Idealism, Individualism and Nationalism in the Social Democratic “The Sunbeam” 1906–1909. In the early twentieth century, the Swedish Social Democratic Youth Movement was possessed of a strong ...
Jimmy Vulovic
doaj   +1 more source

Developing intercultural understanding through Asian-Australian children’s literature. [PDF]

open access: yes, 2014
This PETAA paper discusses how the cross-curriculum priority concerned with developing Asia literacy, namely ‘Asia and Australia’s engagement with Asia’, can be significantly advanced through the study of children’s literature.
Cross, Amy   +3 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy