Results 181 to 190 of about 540,140 (284)

Could Edible Photonic Structures Be an Alternative to Traditional Food Coloring?

open access: yesAdvanced Optical Materials, EarlyView.
What if color in food came from photonic structures? This perspective introduces structural color as a potential next‐generation solution to replace conventional colorants in foods. It discusses edible photonic materials, their unique benefits, and the technological, safety, and consumer acceptance challenges that must be addressed to bring this ...
Miguel A. Cerqueira   +5 more
wiley   +1 more source

Inverse‐Designed on‐Chip Terahertz Three‐Channel Mode and Wavelength Division Demultiplexer

open access: yesAdvanced Photonics Research, EarlyView.
An ultracompact terahertz demultiplexer is developed using a hybrid inverse design that combines genetic algorithms with topology optimization. The device enables simultaneous mode‐ and wavelength‐division multiplexing within a footprint smaller than two wavelengths.
Faqian Chong   +5 more
wiley   +1 more source

Scalable Task Planning via Large Language Models and Structured World Representations

open access: yesAdvanced Robotics Research, EarlyView.
This work efficiently combines graph‐based world representations with the commonsense knowledge in Large Language Models to enhance planning techniques for the large‐scale environments that modern robots will need to face. Planning methods often struggle with computational intractability when solving task‐level problems in large‐scale environments ...
Rodrigo Pérez‐Dattari   +4 more
wiley   +1 more source

The Future of Research in Cognitive Robotics: Foundation Models or Developmental Cognitive Models?

open access: yesAdvanced Robotics Research, EarlyView.
Research in cognitive robotics founded on principles of developmental psychology and enactive cognitive science would yield what we seek in autonomous robots: the ability to perceive its environment, learn from experience, anticipate the outcome of events, act to pursue goals, and adapt to changing circumstances without resorting to training with ...
David Vernon
wiley   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

open access: yesAdvanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu   +14 more
wiley   +1 more source

Indole‐3‐Propionic Acid Improves Alveolar Development Impairment via Targeting VAMP8‐mediated SNAREs Complex Formation in Bronchopulmonary Dysplasia

open access: yesAdvanced Science, EarlyView.
This study aims to evaluate the impact of the tryptophan‐derived metabolite indole‐3‐propionic acid (IPA) on lung development and autophagic flux. IPA alleviates hyperoxia‐induced alveolar arrest by promoting autophagosome‐lysosome fusion via inhibition of VAMP8 phosphorylation, which is suggestive of a promising therapeutic target of BPD.
Beibei Wang   +14 more
wiley   +1 more source

EIF1AX Nucleolar Condensates Enhance Susceptibilities for the Management of Endometrial Cancer

open access: yesAdvanced Science, EarlyView.
This schematic illustrates the mechanism of a senolytic strategy in endometrial cancer. EIF1AX facilitates the incorporation of DDX21 into nucleolar condensates, an event that suppresses rDNA transcription and induces cellular senescence. The compound 2,5‐MeC exploits this pathway by promoting EIF1AX nucleolar translocation and condensate formation ...
Chengyu Lv   +8 more
wiley   +1 more source

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