Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Hirschsprung’s disease in children: a five year experience at a University teaching hospital in northwestern Tanzania [PDF]
, 2014 Joseph B Mabula +5 more
openalex +1 more source
Impact of Prenatal Checkups of Mothers and Immunization of Children on the Health Status of Children (0-3 years) - A Study in Rural areas of Aligarh District, Uttar Pradesh. [PDF]
, 2010 Background and objectives: A survey based study on rural areas of Aligarh District was conducted to assess the prenatal checkups pregnant women and its effects on health status of children between the age of (0-3 years), and immunization received by ...
Alim, Farzana, Jahan, Farhat
core +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Association of Vitamin A Supplementation With Disease Course in Children With Retinitis Pigmentosa [PDF]
, 2018 Eliot L. Berson +4 more
openalex +1 more source
Dental Treatment under General Anesthesia in Healthy and Medically Compromised/Developmentally Disabled Children: A Comparative Study [PDF]
, 2009 Aim: To compare the type, number of procedures and working time of dental treatment provided under dental general anesthesia (DGA) in healthy and medically compromised/developmentally disabled children (MCDD children).
Gonzalez, Cesar D. +5 more
core +1 more source
BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma
FEBS Open Bio, EarlyView.The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru +6 more
wiley +1 more source
Let children be children [PDF]
Journal of Paediatrics and Child Health, 2017 openaire +2 more sources