Results 291 to 300 of about 9,654,900 (378)
COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo+15 more
wiley +1 more source
The Unforgettable "Mel": Pragmatic Inferences Affect How Children Acquire and Remember Word Meanings. [PDF]
Trice K, Saratsli D, Papafragou A, Qi Z.
europepmc +1 more source
Here a transcranial photo‐biomodulation approach is developed using near‐infrared (NIR) laser on hippocampus of mice, revealing significant improvements in learning and memory ability of mice under normal and disease conditions. The improvement results from the high‐density cell‐induced NIR local energy deposition, neuronal activation, and axonogenesis
Wei‐Tong Pan+6 more
wiley +1 more source
Parental Perception of Oral Halitosis in Their Children and Its Effect on Oral Health-Related Quality of Life: A Cross-Sectional Study. [PDF]
Aljudaibi R, Mubaraki S, Baseer MA.
europepmc +1 more source
PRMT1 drives carboplatin resistance and tumor progression in head and neck squamous cell carcinoma (HNSCC) through a novel, methyltransferase‐independent mechanism. It recruits the SWI/SNF complex to activate IGF2BP2, promoting tumor growth and carboplatin resistance. PBX2 upregulates PRMT1, reinforcing this pathway. This study uncovers a non‐catalytic
Shixian Liu+22 more
wiley +1 more source
Trends in socioeconomic inequality in mortality during childhood between 1993 and 2021 in India. [PDF]
Jain A+5 more
europepmc +1 more source
This study reports an innovative strategy to improve the safety of OMVs by shielding them with a sophisticated shell composed of DaFe shell and Au nanoparticles, which not only reduces the toxicity of OMVs during circulation but also enables rapid release of these therapeutically active components in tumor for combined therapy involving glucose ...
Fan Zhang+11 more
wiley +1 more source