Results 71 to 80 of about 4,122,808 (304)
Video Journal of Sports MedicineBackground: Fixed and habitual (obligatory) dislocation of the patella is caused by externally rotated and shortened quadriceps mechanisms. Many surgical techniques have been described to treat this condition, yet there is insufficient evidence favoring ...
Peter Staunton MD +4 more
doaj +1 more source
Annual report of the Massachusetts Memorial Hospitals [PDF]
, 1951 Annual report of the Massachusetts Memorial ...
Massachusetts Memorial Hospitals
core
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Annual report of the Massachusetts Memorial Hospitals [PDF]
, 1956 Annual report of the Massachusetts Memorial ...
Massachusetts Memorial Hospitals
core
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Annual report of the Massachusetts Memorial Hospitals [PDF]
, 1952 Annual report of the Massachusetts Memorial ...
Massachusetts Memorial Hospitals
core
Pediatric Mediastinal Gray Zone Lymphoma With Germline TET2 Heterozygous Variant
Pediatric Blood &Cancer, EarlyView.
Matthew R. Schuelke +9 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Annual report of the Massachusetts Memorial Hospitals [PDF]
, 1957 Annual report of the Massachusetts Memorial ...
Massachusetts Memorial Hospitals
core