Matrix Viscoelasticity Regulates Dendritic Cell Migration and Immune Priming
Advanced Materials, EarlyView.Matrix viscoelasticity is a key mechanical feature of the tumor microenvironment but remains poorly understood in immune regulation. Here, we develop a tunable collagen platform to decouple viscoelasticity from stiffness and show that slow‐relaxing matrices constrain dendritic cell migration by limiting actomyosin‐driven matrix remodeling, thereby ...
Wei‐Hung Jung +6 more
wiley +1 more source
3D Printed Multimaterial Microfluidic Transistors
Advanced Materials Technologies, EarlyView.We introduce a biocompatible, high resolution photopolymer resin that closely mimics the Young's Modulus (elasticity) and reversible stretchability (no hysteresis) of poly(dimethylsiloxane) (PDMS), enabling the fabrication of microfluidic transistors (i.e., microvalves capable of proportional amplification) by multimaterial stereolithography (mSLA ...
Alireza Ahmadianyazdi +7 more
wiley +1 more source
How many children have palliative care needs and which of them are less likely to be actively seen by services? A cross-sectional analysis of survey data. [PDF]
BMJ Paediatr OpenFrench M, Walshe C, Garner A.
europepmc +1 more source
, 2007 It is now over 30 years since the original federal Child Care Act was passed in the dying days of the McMahon Liberal government but funding and policy issues are still confused and contested. Many more child care places exist and more funding is provided, but Australia still lacks an integrated national childcare system that recognises the importance ...
openaire +1 more source
Respiratory Signal Processing and Analysis Using Flexible Capacitive Sensor Data
Advanced Materials Technologies, EarlyView.Capacitive pressure sensors based on poly(glycerol sebacate) (PGS) substrates are developed for continuous, non‐invasive respiratory monitoring. Integrated with a signal processing algorithm, they enable accurate tracking of thoracic expansion and retraction.
Bernardo A. Vicente +3 more
wiley +1 more source
What Influences Speech Pathology Practice for Children with Complex Communication Needs from Multilingual Families? An Australian Perspective. [PDF]
Int J Lang Commun DisordSkinner N, Barnes S.
europepmc +1 more source
Advanced Science, EarlyView.An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang +10 more
wiley +1 more source
"Disconnected From Everyone and Everything Around Them": A Mixed Method Study to Explore the Perspectives of Children With Language Difficulties and Their Caregivers On Mental Health Concerns and Mental Health Support. [PDF]
Int J Lang Commun DisordWilmot A +9 more
europepmc +1 more source
Advanced Science, EarlyView.Nitrosyl heme emerges as an extracellular nitrodilator that dilates arteries without crossing the cell membrane. Instead, heme‐NO mobilizes NO moieties from a preformed intracellular NO store within vascular smooth muscle, providing both functional and chemical evidence for the NANOS model, revealing a previously unrecognized mechanism of arterial ...
Taiming Liu +9 more
wiley +1 more source
How to cut child mortality in half again: making primary healthcare work. [PDF]
J Glob HealthCarai S, Jullien S.
europepmc +1 more source