Results 61 to 70 of about 2,826,722 (313)

Marketing library services to children and young people [PDF]

open access: yes, 2006
This paper discusses the future of Schools Library Services in the North West region of England based on a research project recently undertaken by the Centre for the Public Library and Information in Society at the University of Sheffield on behalf of ...
Train, B., Wilson, K.
core   +1 more source

Predicting the Future Burden of Renal Replacement Therapy in Türkiye Using National Registry Data and Comparative Modeling Approaches

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic kidney disease is a growing public health problem worldwide, and the number of patients requiring renal replacement therapy is steadily increasing. Türkiye has experienced a similar rise in both the incidence and prevalence of renal replacement therapy over the past decades; however, national‐level projections of future ...
Arzu Akgül   +2 more
wiley   +1 more source

Treatment-Emergent Mania in a Prepubertal Boy

open access: yesCase Reports in Psychiatry, 2018
Bipolar disorder among children has gained acceptance as a diagnostic entity but continues to pose diagnostic and management challenges due to the developmental differences in children and inadequate evidence for pharmacological management.
Dulangi Maneksha Amerasinghe Dahanayake   +1 more
doaj   +1 more source

Partnering with Medicaid to Advance and Sustain the Goals of the Child Welfare System [PDF]

open access: yes, 2016
The purpose of this paper is to serve as a practical guide for child welfare directors who are looking to expand or sustain services for the children and families that they serve.
Deborah S. Harburger   +5 more
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Education and social service use patterns of children and youth with neurodevelopmental disorders

open access: yesInternational Journal of Population Data Science, 2018
Introduction This study uses linked administrative data to identify Albertan children and youth (aged 0 to 25 years) with Autism Spectrum Disorder (ASD), Cerebral Palsy (CP) or Fetal Alcohol Spectrum Disorder (FASD), and to examine their government ...
Ruiting Jia   +4 more
doaj   +1 more source

"Why does it happen like this?". Consulting with users and providers prior to an evaluation of services for children with life-limiting conditions and their families [PDF]

open access: yes, 2014
Background: Children with life-limiting conditions and their families have complex needs. Evaluations must consider their views and perspectives to ensure care is relevant, appropriate and acceptable.
Hacking, Suzanne, Hunt, Anne
core  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Implementation barriers and enablers of midwifery group practice for vulnerable women: a qualitative study in a tertiary urban Australian health service

open access: yesBMC Health Services Research, 2022
Background Maternity services have limited formalised guidance on planning new services such as midwifery group practice for vulnerable women, for example women with a history of substance abuse (alcohol, tobacco and other drugs), mental health ...
Patricia A Smith   +4 more
doaj   +1 more source

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