Results 131 to 140 of about 784,997 (355)

HIDF: Integrating Tree‐Structured scRNA‐seq Heterogeneity for Hierarchical Deconvolution of Spatial Transcriptomics

Advanced Science, EarlyView.
The prevailing neglect of cellular hierarchies in current spatial transcriptomics deconvolution often obscures cellular heterogeneity and impedes the identification of fine‐grained subtypes. To address this issue, HIDF employs a cluster‐tree and dual regularization to systematically model cellular hierarchical structures.
Zhiyi Zou, Yuting Bai, Bo Wang, Wanwan Shi, Xiao Liang, Jiawei Luo   +5 more
wiley   +1 more source

Education of Children with Disabilities: Voices from Around the World [PDF]

, 2015
Education of Children with Disabilities: Voices from Around the World combines research on children with disabilities and women/girls with disabilities.
Bergquist, Carol, Haynes, Cary, Johnson, Charles, Krinhop, Kash, Peairson, Shannon   +4 more
core   +2 more sources

A Wireless, Battery‐Free Artificial Throat Patch with Deep Learning for Emotional Speech Recognition

Advanced Science, EarlyView.
In this work, Xu and co‐workers develop a wireless, battery‐free artificial throat patch system (ATPS) consisting of a carbon nanotube‐based thin‐film strain sensor and a miniaturized flexible printed circuit board, to enable real‐time sensing of throat signals.
Bingxin Xu, Guanming Lin, Xiaohui Hong, Chuting Liu, Xinyi Qu, Kangjian Jiao, Lei Zhang, Bingzhe Xu, Jun Yan, Yancong Qiao, Xudong Lin   +10 more
wiley   +1 more source

Genetic Diagnosis and Discovery Enabled by Large Language Models

Advanced Science, EarlyView.
We demonstrate that large language models (LLMs) can facilitate genetic diagnosis and discovery. LLMs were used to solve four types of genetic problems of sequentially increased complexity. An LLM‐based pipeline could analyze genetic variants in the genomic sequences of human hearing loss or rare genetic disease patients and assist in identifying ...
Tao Tu, Khaled Saab, Weida Liu, Zhouqing Fang, Zhuanfen Cheng, Svetolik Spasic, Maja Djurisic, Hiroaki Mohri, Wenlong Ren, Anil Palepu, Juraj Gottweis, Alan Karthikesalingam, Kavita Kulkarni, Annalisa Pawlosky, Devon Bonner, Elijah Kravets, Shruti Marwaha, Hector R. Mendez, Matthew T. Wheeler, Jonathan A. Bernstein, Undiagnosed Diseases Network, Cheng‐Yu Tsai, Chen‐Chi Wu, Konstantina M. Stankovic, Vivek Natarajan, Gary Peltz   +25 more
wiley   +1 more source

Impact of Sensory Adapted Dental Environment on Children with Developmental Disabilities [PDF]

, 2018
Purpose: This was a pilot study assessing the impact of a sensory adapted dental environment (SADE) on children with developmental disabilities (DD) receiving routine dental care.
Kim, Gail
core   +1 more source

The Individuals With Disabilities Education Act (IDEA) for Children With Special Educational Needs

Pediatrics, 2015
The pediatric health care provider has a critical role in supporting the health and well-being of children and adolescents in all settings, including early intervention (EI), preschool, and school environments. It is estimated that 15% of children in the
P. Lipkin, J. Okamoto
semanticscholar   +1 more source

Cortical Somatostatin Neurons Regulate Seizure Susceptibility via MINAR1/Gαs–cAMP Signaling

Advanced Science, EarlyView.
Our study identifies MINAR1 as a novel regulator of cortical interneuron excitability and seizure susceptibility. MINAR1 is preferentially expressed in SST+ interneurons. Genetic ablation of MINAR1 leads to seizure hypersensitivity, reduced SST+ neuron excitability, and impaired Gαs–cAMP signaling, disrupting the E/I balance.
Wei‐Tang Liu, Zhi‐Bin Hu, Ling Hu, Yu‐Bing Wang, Qiong Zhang, Ning‐Ning Song, Xi‐Yue Liu, Jia‐Yin Chen, Hong‐Wen Zhu, Bing‐Yao Zhou, Yun‐Chao Tao, Li Zhao, Ze‐Xuan Li, Yi‐Wei Li, Jia‐Qi Chen, Si‐Xin Tu, Cong‐Cong Qi, Sai‐Dan Ding, Gang Peng, Lin Xu, Yu‐Qiang Ding   +20 more
wiley   +1 more source

Iterative Data Curation for Machine Learning‐Based Inverse Design of Active Composite Plates for Four‐Dimensional Printing

Advanced Intelligent Systems, EarlyView.
A machine learning framework is developed for the inverse design of 4D‐printed active composite plates. It utilizes a forward model to predict shapes from patterns and an inverse model to suggest initial patterns for desired shapes. This framework integrates a genetic algorithm to refine the predicted patterns, ensuring higher accuracy in achieving ...
Teerapong Poltue, Chao Zhang, Frédéric Demoly, Kun Zhou, H. Jerry Qi   +4 more
wiley   +1 more source

"Look Mum, no hands!" : the effects of increasing opportunities for choice-making and independence for children with disabilities when using a Riding for the Disabled programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Arts in Psychology at Massey University [PDF]

, 2005
Many non-disabled people take for granted their ability to choose when they receive help from others. Those with disabilities are often denied this choice, having minimal control over their lives. Increasing literature and research advocate that children
Bingham, Amie Olga
core  

Facilitators and barriers to neighborhood social integration

American Journal of Community Psychology, EarlyView.
Abstract Social isolation has reached concerning rates, particularly in the wake of the COVID‐19 pandemic. Social integration is critical to combatting social isolation and loneliness by promoting a sense of community and belonging. Yet, most existing research centers on fostering close personal relationships within family and friend networks.
Joelle Fuchs, Deena Shariq, Emily Yang, Giselle Maya, Taylor L. Wilds, Collin W. Mueller, Arianna M. Gard   +6 more
wiley   +1 more source