Results 171 to 180 of about 99,390 (298)

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan   +2 more
wiley   +1 more source

Tranexamic Acid in Lower Extremity Endoprosthetic Reconstruction for Oncologic Indications: A Retrospective Comparative Study of 617 Patients

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Background and Objectives While tranexamic acid (TXA) reduces blood loss in orthopedic surgery, thromboembolic concerns in cancer patients have limited adoption in orthopedic oncology. This study evaluated TXA efficacy and safety in patients undergoing endoprosthetic reconstruction for oncologic indications.
Stephen W. Chenard   +10 more
wiley   +1 more source

Point‐of‐Care Ultrasound for the Diagnosis of Hip Effusion in Children Presenting to the Emergency Department With Atraumatic Limp or Hip Pain: A Scoping Review

open access: yesJournal of Ultrasound in Medicine, EarlyView.
This study reviews the evidence for point‐of‐care ultrasound (POCUS) for the detection of hip effusion in children presenting to the emergency department with atraumatic limp or hip pain. A scoping review was conducted using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses Extension for Scoping Review (PRISMA‐ScR) guideline ...
Nigel Chan   +3 more
wiley   +1 more source

Clinical Features and Therapeutic Outcomes in Pyoderma Gangrenosum: A Prospective Cohort Study

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Background Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis highly associated with systemic comorbidities. Accurate diagnosis and treatment remain challenging due to its rarity and clinical mimickers. Objectives To evaluate demographic, clinical features and treatment outcomes in patients referred with suspected PG at a tertiary ...
David Croitoru   +13 more
wiley   +1 more source

Approach to Nail Pitting in Pediatric and Adolescent Patients: A Dermatology Perspective

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT This narrative review aims to discuss the etiologies of nail pitting in pediatric and adolescent patients, while providing a framework for further evaluation of possible underlying systemic conditions and their clinical findings from a dermatologic standpoint.
Elizabeth Botto   +3 more
wiley   +1 more source

Risk Factors Associated With the Number of Symptoms and Distress Caused by Genitourinary Syndrome of Menopause in Taiwanese Women

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT A high percentage of women who undergo the transition to postmenopause experience both menopausal symptoms and genitourinary syndrome of menopause (GSM). However, GSM is often underdiagnosed. This research aims to identify risk factors that may influence the number of GSM symptoms and whether they cause distress in Taiwanese women > 45 years ...
Shu‐Fang Su   +2 more
wiley   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia   +3 more
wiley   +1 more source

COVID-19 in children with rheumatic diseases (RD) in the spanish national cohort EPICO-AEP

open access: yes, 2020
Calvo C   +9 more
europepmc   +1 more source

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