Results 111 to 120 of about 1,908,578 (405)

piR‐RCC Suppresses Renal Cell Carcinoma Progression by Facilitating YBX‐1 Cytoplasm Localization

Advanced Science, EarlyView.
PIWI‐interacting RNAs (piRNAs), a novel category of small non‐coding RNAs, have been implicated in the development of various diseases. This study explores the tumor‐suppressive mechanism of a downregulated piRNA (designated piR‐RCC) in renal cell carcinoma (RCC), and provides a delivery strategy targeting RCC tumor by constructing a cell membrane ...
Ruyue Wang, Fan Li, Yudong Lin, Zeyi Lu, Wenqin Luo, Zhehao Xu, Ziwei Zhu, Yi Lu, Xudong Mao, Yang Li, Zhinian Shen, Haohua Lu, Yining Chen, Liqun Xia, Mingchao Wang, Lifeng Ding, Gonghui Li   +16 more
wiley   +1 more source

Desarrollo de la educación parvularia en Chile - Preschool education development in Chile

História da Educação, 2011
DESENVOLVIMENTO DA EDUCAÇÃO PRÉ-ESCOLAR NO CHILEResumoA educação pré-escolar no Chile tem início na segunda metade do século 19, especialmente por influência alemã, trazida ao país por José Abelardo Núñez.
Jaime Caiceo, Chile
doaj  

Personalization, privatization, and campaign strategies in newspaper coverage of two Chilean presidential elections, 1989-2009

Communication & Society (Formerly Comunicación y Sociedad), 2014
We investigate the evolution of the coverage of political campaigns in Chile, through a content analysis of the issues highlighted in four national newspapers in the 1989 and 2009 campaigns.
William Porath, José-Joaquín Suzuki, Tania-Marie Ramdohr   +2 more
doaj   +1 more source

Exact Random Walk Distributions using Noncommutative Geometry [PDF]

, 1997
Using the results obtained by the non commutative geometry techniques applied to the Harper equation, we derive the areas distribution of random walks of length $ N $ on a two-dimensional square lattice for large $ N $, taking into account finite size contributions.
arxiv   +1 more source

Engineering Electron Transfer Flux between Cytochrome P450 Enzyme and P450 Reductase to Enhance Serotonin Production in Escherichia Coli

Advanced Science, EarlyView.
The electron transfer flux in CPR‐P450 catalytic system is systematically engineered through: i) enhancing electron transfer rate by redesigning the putative electron transfer pathway of CPR; ii) improving electron‐receiving rate by evolving the heme domain of tryptophan‐5‐hydroxylase (T5H); iii) enlarging electron supply by fine‐tuning NADPH synthesis.
Wenzhao Xu, Pengling Wei, Lirong Chen, Ling Gao, Xiaole Xia   +4 more
wiley   +1 more source

La proyección colonial de Chile a la Patagonia Insular en el siglo XVIII

Anuario de Estudios Americanos, 2011
Este artículo presenta las consecuencias geopolíticas del naufragio de la fragata inglesa Wager y la recalada de otro barco, el Anna, que formaban parte de la flota de George Anson, en las costas de la Patagonia Occidental Insular en 1741.
María Ximena Urbina Carrasco
doaj   +1 more source

Seyfert 1 mutation of the classical Seyfert 2 nucleus NGC 7582 [PDF]

, 1999
We report the transition towards a type 1 Seyfert experienced by the classical type 2 Seyfert nucleus in NGC 7582. The transition, found at most 20 days from its maximum peak, presents a unique opportunity to study these rare events in detail. At maximum the Ha line width is of about 12000 km/s. We examine three scenarios that could potentially explain
arxiv   +1 more source

Chile Fiscal Policy Management [PDF]

, 2013
A budget surplus arises in a country when the total revenue earnings surpass expenditures in a particular financial year. Having a budget surplus is very important in the sense that it brings about a decrease in the net public debt, while the public debt
Betancourt, Erico Wulf, Piasecki, Ryszard   +1 more
core   +2 more sources

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

Advanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng, Yunhao Pan, Fengyuan Qian, Diya Liu, Danrong Ye, Bolin Yu, Seng Zhong, Wenfang Zheng, Xuehui Wang, Baian Zhou, Yuying Wang, Lin Fang   +11 more
wiley   +1 more source

Come together over me: Cells that form the dermatocranium and chondrocranium in mice

The Anatomical Record, EarlyView., 2023
Abstract Most bone develops either by intramembranous ossification where bone forms within a soft connective tissue, or by endochondral ossification by way of a cartilage anlagen or model. Bones of the skull can form endochondrally or intramembranously or represent a combination of the two types of ossification.
M. Kathleen Pitirri, Joan T. Richtsmeier, Mizuho Kawasaki, Abigail P. Coupe, Susan Motch Perrine, Kazuhiko Kawasaki   +5 more
wiley   +1 more source