Results 121 to 130 of about 1,947,105 (313)

A dsRNA Viral Transcriptional Regulator Evades Innate Immunity by Hijacking Host CoTranscription Factor DHX9

open access: yesAdvanced Science, EarlyView.
This study identifies a new viral mechanism by a viral protein σ3 that functions as a vTR to suppress NF‐κB gene expression via its direct interaction with the host helicase DHX9. Through their interaction, σ3 not only impairs the initial recruitment of Pol II but also affects Pol II pause‐release and ultimately suppresses NF‐κB gene expression ...
Xueyang Pang   +12 more
wiley   +1 more source

HISTORIA, ARCHIVO Y MULTIDISCIPLINA EN CHILE [PDF]

open access: diamond, 2015
Rodrigo Ruz Zagal, Luis Galdames Rosas
openalex   +1 more source

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu   +12 more
wiley   +1 more source

A decade lost and found: Mexico and Chile in the 1980s [PDF]

open access: yes
Chile and Mexico experienced severe economic crises in the early 1980s. This paper analyzes four possible explanations for why Chile recovered much faster than did Mexico.
Kehoe   +4 more
core  

Familia, género y violencia económica: incumplimiento de las pensiones de alimentos en Chile

open access: yesÍconos
El pago de las pensiones alimenticias es uno de los principales desafíos en torno a la equidad de género y a la justicia económica. Cifras recientes demuestran que el 84 % de las pensiones alimenticias decretadas por los tribunales de familia son ...
Martina Yopo-Díaz   +1 more
doaj   +1 more source

A Rationally Engineered Spleen‐Tropic One‐Component Lipid‐mRNA Complex (OncoLRC) for Cancer Vaccines

open access: yesAdvanced Science, EarlyView.
OncoLRC, a one‐component lipid‐mRNA complex, enables efficient spleen‐targeted delivery at an exceptionally low lipid‐to‐mRNA mass ratio (1.5:1), robustly activates immune responses, inhibits tumor growth, and synergizes with checkpoint blockade, presenting a next‐generation platform for mRNA vaccines.
Qimeng Yin   +4 more
wiley   +1 more source

A Real Time Evaluation of the Central Bank of Chile GDP Growth Forecasts. [PDF]

open access: yes
In this paper we evaluate the Central Bank of Chile annual GDP growth forecasts over the period 1991-2009 using a real-time database. We compare the Central Bank of Chile forecasts with those of the Survey of Professional Forecasters (SPF), Consensus ...
Pablo Pincheira
core  

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