Results 71 to 80 of about 344,642 (309)

Cell Contractile Force‐Mediated Morphogenetic Tissue Engineering via 4D Printed Degradable Hydrogel Scaffolds

open access: yesAdvanced Science, EarlyView.
Through the actuation of cell contractile forces, geometrically complex structures are formed via a bioprinted, rapidly degrading cell‐laden hydrogel system, resulting in cell‐only condensation within a few days of culture. This system supports stem cell differentiation down different lineages and new tissue formation, such as chondrogenesis and ...
Aixiang Ding   +4 more
wiley   +1 more source

Amphiregulin and Epiregulin Confer Radioresistance in Esophageal Squamous Cell Carcinoma Through Oxidative Phosphorylation

open access: yesAdvanced Science, EarlyView.
Oxidative phosphorylation (OXPHOS) activity serves as a critical metabolic determinant of radiotherapy outcomes in esophageal squamous cell carcinoma (ESCC). The CEBPB/AREG/EREG axis drives radioresistance in ESCC by reprogramming OXPHOS. AREG and EREG function as predictive biomarkers for nCRT response and prognosis of ESCC patients.
Zhang Lin   +15 more
wiley   +1 more source

La proyección colonial de Chile a la Patagonia Insular en el siglo XVIII

open access: yesAnuario de Estudios Americanos, 2011
Este artículo presenta las consecuencias geopolíticas del naufragio de la fragata inglesa Wager y la recalada de otro barco, el Anna, que formaban parte de la flota de George Anson, en las costas de la Patagonia Occidental Insular en 1741.
María Ximena Urbina Carrasco
doaj   +1 more source

Covid-19 in South America: clinical and epidemiological characteristics among 381 patients during the early phase of the pandemic in Santiago, Chile [PDF]

open access: gold, 2020
Macarena R. Vial   +10 more
openalex   +1 more source

Morphine Tolerance Gated through EZH2‐Mediated Suppression of Trpc5 in Spinal GABAergic Interneurons in Male Mice

open access: yesAdvanced Science, EarlyView.
Chronic morphine suppresses Trpc5 in spinal GABAergic interneurons via EZH2‐mediated histone modification, reducing Ca2+ influx and GABA release. TRPC5 activation enhances morphine analgesia, while EZH2 inhibition restores efficacy and reverses tolerance.
Li Wan   +9 more
wiley   +1 more source

ACUERDO ARGENTINA CHILE

open access: yesAportes para la Integración Latinoamericana, 2017
Acuerdo Argentina -  Chile Tratado de maipú de integración y cooperación argentina - chile, Maipú, Chile, 30 de octubre 2009 Declaración presidencial  Conjunta argentina – chile, Santiago de Chile, Chile, 29 y 30 de octubre ...
Repüblica Argentina República de Chile
doaj  

Los Lamini (Cetartiodactyla: Camelidae) extintos del yacimiento de Pilauco (Norpatagonia chilena): aspectos taxonómicos y tafonómicos preliminares

open access: yesEstudios Geologicos, 2013
Se presenta la descripción y asignación taxonómica preliminar de los restos de Lamini recuperados en el sitio paleontológico de Pilauco (Pleistoceno tardío) ubicado en el sur de Chile.
Rafael Labarca Encina   +2 more
doaj   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

open access: yesAdvanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang   +17 more
wiley   +1 more source

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