Results 131 to 140 of about 20,714 (300)

Cells Dynamically Adapt Their Nuclear Volumes and Proliferation Rates During Single to Multicellular Transitions

open access: yesAdvanced Science, EarlyView.
It is currently not well understood how cells regulate basic properties, e.g., volume and mechanics within dense multicellular environments like tumors. Here, we show that different cell types of cancer and also normal cells largely decrease their nuclear and cellular volumes in emerging cell clusters and that this is partly driven by cell cycle shifts.
Vaibhav Mahajan   +13 more
wiley   +1 more source

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Analysis and Market Prospects of a Traditional Calabrian Product [PDF]

open access: yes
The strategies for exploiting typical production represents a theme of great interest, above all in the measure in which exploitation brought about via adequate marketing strategies allows these products to shed their anonymity.
Gulisano, Giovanni, Platania, Marco
core   +1 more source

An Analysis of Market Integration for Selected Vegetables in Indonesia [PDF]

open access: yes, 1997
IndonesianSayur-sayuran adalah salah satu jenis komoditas penting di Indonesia yang termasuk dalam penyurnbang devisa ekspor nonmigas di Indonesia.
Munir, A. (Achmad)   +3 more
core  

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

open access: yesAdvanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li   +13 more
wiley   +1 more source

Combining Ability of Several Introduced and Local Chilli Pepper (Capsicum Annuum L.) Genotypes and Heterosis of the Offsprings [PDF]

open access: yes, 2010
The objective of the study was to identify the combining ability of several introduced and local chilli genotypes and heterosis effects of their offsprings, as a result of the hybridisation process.
Sitaresmi, T. (Trias)   +2 more
core  

An appraisal of Chilli production technology adopted by the farmers of Punjab

open access: yesIndian Journal of Extension Education, 2022
null Sunidhi   +2 more
openaire   +1 more source

Palmitic Acid Promotes Antiviral Innate Immunity via ZDHHC20‐Mediated CMPK2 Palmitoylation

open access: yesAdvanced Science, EarlyView.
Metabolites have important functions in innate immune activation and regulation. Wang et al. uncover metabolic regulation of antiviral immunity through CMPK2 palmitoylation, which regulates CMPK2 mitochondrial localization and is promoted by ZDHHC20 but reversed by PPT1, inhibition of which antagonizes viral infection in mice.
Yujia Wang   +4 more
wiley   +1 more source

Chilli-YOLO: An Intelligent Maturity Detection Algorithm for Field-Grown Chilli Based on Improved YOLOv10

open access: yes智慧农业
[Objective]In modern agriculture, the rapid and accurate detection of chillies at different maturity stages is a critical step for determining the optimal harvesting time and achieving intelligent sorting of field-grown chillies. However, existing target
SI Chaoguo   +4 more
doaj   +1 more source

MUDIM Enterprise: Finding the right strategy [PDF]

open access: yes, 2017
Despite Shaarani’s efforts in positioning MUDIM as one of the successful Small and Medium Enterprises (SMEs) in Malaysia, his mind was not at peace.
Ahmad Arshad, Darwina   +2 more
core  

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