Results 81 to 90 of about 62,175 (302)

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Nut crop yield records show that budbreak-based chilling requirements may not reflect yield decline chill thresholds [PDF]

International Journal of Biometeorology, 2014
Warming winters due to climate change may critically affect temperate tree species. Insufficiently cold winters are thought to result in fewer viable flower buds and the subsequent development of fewer fruits or nuts, decreasing the yield of an orchard or fecundity of a species.
Pope, Katherine S, Dose, Volker, Da Silva, David, Brown, Patrick H, DeJong, Theodore M   +4 more
openaire   +5 more sources

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Effect of photon flux density on bud dormancy release in Norway spruce seedlings.

Silva Fennica, 1991
The effect of photon flux density on bud dormancy release in two-year-old seedlings of Norway spruce ( (L.) H. Karst.) was examined. The seedlings were first chilled for 0–21 weeks under natural conditions and then forced in a warm greenhouse either in
Höyhtyä, Riitta, Hänninen, Heikki
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Track Record on Takings Legislation: Lessons from Democracy\u27s Laboratories [PDF]

, 2008
This report by the Georgetown Environmental Law & Policy Institute, entitled The Track Record on Takings Legislation: Lessons from Democracy\u27s Laboratories, examines the experiences of Florida, Oregon, and several other states with legislation ...
Echeverria, John D., Hansen-Young, Thekla   +1 more
core   +1 more source

Assessment of agroclimatic suitability of apple orchards in Himachal Pradesh under changing climate

Journal of Agrometeorology, 2017
Apple crop require adequate chilling for breaking its winter dormancy for a usual spring growth. In this study, suitability of apple production was assessed by using GIS based UTAH chill unit model for tactical and strategic adaptation options under ...
JYOTI SINGH, N. R. PATEL
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Developing Sous Vide/Freezing Systems for Ready-Meal omponents [PDF]

, 2005
End of project reportSous vide cooking involves sealing raw or par-cooked food in a vacuumised laminated plastic pouch or container, cooking by controlled heating, rapid chilling and then re-heating for consumption. The chilled storage period is up to 21
Bourke, Paula, Carbonell, Serge, Gormley, Ronan T., O'Beirne, David, Oliveira, Jorge, Tansey, Fergal   +5 more
core  

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source