Results 91 to 100 of about 7,776 (287)

Modulation of miR‐23b Wnt/β‐catenin Axis Strengthens Endothelial Barrier Properties

open access: yesAdvanced Science, EarlyView.
Early blood‐brain barrier (BBB) disruption contributes to stroke and CNS disease pathology. miR‐23b was identified as a regulator of BBB integrity in brain endothelial cells. Inhibition of miR‐23b enhanced barrier‐associated properties, promoted repair‐related signaling, and reduced BBB leakage in experimental stroke models, supporting further ...
Victor Anthony Martinez   +16 more
wiley   +1 more source

Metazoan Parasite Communities of Two Sympatric Shortnose Chimeras (Holocephali: Chimaeridae) from Deep Waters Associated with the Humboldt Current System: Ancient Fishes Harbor Ancient Parasites

open access: yesDiversity
A total of 61 specimens of deep-sea chimaeras (Hydrolagus melanophasma = 41; Chimaera sp. = 20) were obtained during September 2017 as by-catch of the local fishery of the Patagonian toothfish (Dissostichus eleginoides, Pisces: Nototheniidae) along the ...
Marcelo E. Oliva   +3 more
doaj   +1 more source

Synthetic Toll‐Like Receptors for Control of Innate Immunity With Far‐Red Light

open access: yesAdvanced Science, EarlyView.
Synthetic Toll‐like receptors (TLRs) are engineered by replacing their natural sensing regions with a far‐red‐light‐responsive module from a bacterial phytochrome. These synthetic receptors enable light‐controlled regulation of immune signaling in mammalian cells.
Anna V. Leopold, Vladislav V. Verkhusha
wiley   +1 more source

Chimaera monstrosa

open access: yes, 2007
Chimaera monstrosa Linnaeus, 1758 Aegean Sea: 100-530 (1 spc.), 24.01.1969, Gökova Bay, trawl, 450 m, M. Demir; 100-1 (1 spc.), 15.02.1991, Saros Bay, N.
Nurettin Meriç   +2 more
core   +1 more source

The global Mycobacterium chimaera outbreak

open access: yesMicrobiologia Medica, 2019
Infections due to Mycobacterium chimaera associated with a heater-cooler device used during the open-heart surgery have been reported worldwide. These cases represent the first outbreak caused by a non-tuberculous mycobacterium at a global level. Salient
Enrico Tortoli
doaj   +1 more source

Auto‐Downregulation of the Florigen FT Production Prevents Precocious Flowering in Plants

open access: yesAdvanced Science, EarlyView.
This study shows that the leaf vein‐expressed FD complexes with the florigen FT to bind DNA motifs in FT promoter, which antagonizes CONSTANS‐mediated FT activation to feedback down‐regulate FT expression. This prevents an excessive induction of FT expression by inductive photoperiods, thereby precluding precocious transition to flowering in ...
Shu Tian, Xiao Luo, Bowen Cui, Yuehui He
wiley   +1 more source

Draft Genome Sequence of Mycobacterium chimaera Type Strain Fl-0169

open access: yes, 2017
We report here the draft genome sequence of the type strain Mycobacterium chimaera Fl-0169, a member of the Mycobacterium avium complex (MAC). M. chimaera Fl-0169 T
Vasily Tokarev   +7 more
core   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

open access: yesAdvanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li   +8 more
wiley   +1 more source

A Disulfide‐Sticker Strategy for Marine Adhesive Coatings: From Deciphering Self‐Assembly Mechanism to Functional Application in Hair Regeneration

open access: yesAdvanced Science, EarlyView.
A disulfide‐sticker strategy, coupled with Ca2+ coordination, drives the hierarchical self‐assembly of a recombinant scallop adhesive protein into fishnet‐like nanostructures, affording a coating with versatile wet adhesion and intrinsic antioxidant activity. This biocompatible coating markedly promotes hair regeneration by activating follicular niches,
Lulu Wang   +7 more
wiley   +1 more source

Chimaera

open access: yes, 2014
In her thesis Chimaera, Charlotte Greenbaum uses the hybridization of women and animals in order to investigate mental illness through a feminist lens.
Greenbaum, Charlotte E
core   +1 more source

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