Results 31 to 40 of about 136,848 (282)

Cognitive chimera states in human brain networks [PDF]

Science Advances, 2018
Researchers describe human brain organization using a framework that measures patterns of synchrony across cognitive systems. The human brain is a complex dynamical system, and how cognition emerges from spatiotemporal patterns of regional brain activity
Kanika Bansal, J. Garcia, S. Tompson, T. Verstynen, J. Vettel, S. Muldoon   +5 more
semanticscholar   +1 more source

Molecular mechanisms underlying catalytic activity of delta 6 desaturase from Glossomastix chrysoplasta and Thalassiosira pseudonana[S]

Journal of Lipid Research, 2018
Delta 6 desaturase (FADS2) is a critical bifunctional enzyme required for PUFA biosynthesis. In some organisms, FADS2s have high substrate specificity, whereas in others, they have high catalytic activity. Previously, we analyzed the molecular mechanisms
Haisu Shi, 史海 粟, Rina Wu, 乌日 娜, Yan Zheng, 郑 艳, Xiqing Yue, 岳喜 庆   +7 more
doaj   +1 more source

ASCVac-1, a Multi-Peptide Chimeric Vaccine, Protects Mice Against Ascaris suum Infection

Frontiers in Immunology, 2021
Control of human ascariasis, the most prevalent neglected tropical disease globally affecting 450 million people, mostly relies on mass drug administration of anthelmintics.
Ana Clara Gazzinelli-Guimarães, Denise Silva Nogueira, Chiara Cássia Oliveira Amorim, Fabrício Marcus Silva Oliveira, Anderson Coqueiro-Dos-Santos, Samuel Alexandre Pimenta Carvalho, Lucas Kraemer, Fernando Sérgio Barbosa, Vanessa Gomes Fraga, Flaviane Vieira Santos, Joseane Camilla de Castro, Remo Castro Russo, Milena Apetito Akamatsu, Paulo Lee Ho, Maria Elena Bottazzi, Peter J. Hotez, Bin Zhan, Daniella Castanheira Bartholomeu, Lilian Lacerda Bueno, Ricardo Toshio Fujiwara   +19 more
doaj   +1 more source

Epitope Specificity of HLA Class I Alloantibodies in Indian Renal Transplant Patients: A Single-Center Study

Transplantology
Background/Objectives: Epitope-based matching has emerged as a refined approach for assessing donor–recipient compatibility in renal transplantation.
Vikash Chandra Mishra, Dinesh Chandra, Ritu Sharma, Diksha Dhuliya, Vimarsh Raina   +4 more
doaj   +1 more source

Androgen receptor degradation by the proteolysis-targeting chimera ARCC-4 outperforms enzalutamide in cellular models of prostate cancer drug resistance

Communications Biology, 2018
The androgen receptor is a major driver of prostate cancer and inhibition of its transcriptional activity using competitive antagonists, such as enzalutamide remains a frontline therapy for prostate cancer management.
J. Salami, Shanique Alabi, Ryan R Willard, N. Vitale, Jing Wang, Hanqing Dong, Meizhong Jin, D. McDonnell, A. Crew, T. Neklesa, C. Crews   +10 more
semanticscholar   +1 more source

Susceptibility of Caribbean Brain Coral Recruits to Stony Coral Tissue Loss Disease (SCTLD)

Frontiers in Marine Science, 2022
Stony coral tissue loss disease (SCTLD) has devastated coral populations along Florida’s Coral Reef and beyond. Although widespread infection and mortality of adult colonies have been documented, no studies have yet investigated the susceptibility of ...
Olivia M. Williamson, Caroline E. Dennison, Keri L. O’Neil, Andrew C. Baker   +3 more
doaj   +1 more source

Non-HLA Antibodies in Kidney Transplantation: Pathogenesis, Clinical Impact, and Management Approaches

Transplantology
Antibody-mediated rejection is a critical factor in acute and chronic allograft rejection, with Human Leukocyte Antigen as the primary target of the humoral immune response in kidney transplants.
Vikash Chandra Mishra, Dinesh Chandra, Vimarsh Raina   +2 more
doaj   +1 more source

Histocompatibility Testing: A Fundamental Aspect of Renal Transplant Workup

Transplantology
Histocompatibility testing is pivotal in any renal transplantation workup, aimed at enhancing prospective donor recipient compatibility and improving transplant outcomes.
Vikash Chandra Mishra, Dinesh Chandra, Vimarsh Raina   +2 more
doaj   +1 more source

The proposed channel-enzyme transient receptor potential melastatin 2 does not possess ADP ribose hydrolase activity

eLife, 2016
Transient Receptor Potential Melastatin 2 (TRPM2) is a Ca2+-permeable cation channel essential for immunocyte activation, insulin secretion, and postischemic cell death.
Iordan Iordanov, Csaba Mihályi, Balázs Tóth, László Csanády   +3 more
doaj   +1 more source

How African Higher Education Institutions Can Weather a Pandemic [Munyao, Martin, ed. Online Learning, Instruction, and Research in Post-Pandemic Higher Education in Africa]

African Christian Theology
[BOOK REVIEW ESSAY: Munyao, Martin, ed. Online Learning, Instruction, and Research in Post-Pandemic Higher Education in Africa. Foreword by George John Law.
Felix Chimera Nyika
doaj   +1 more source