Results 21 to 30 of about 10,179,531 (360)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

中国藏羚羊保护现状

open access: yes野生动物学报, 1999
由于国际上对藏羚羊绒贸易的干扰,中国一级保护动物藏羚羊正面临着偷猎和走私的严重威胁,种群数量正急剧下降.中国政府提出请国际社会给予关注,尽早取缔对藏羚羊绒的国际贸易,保护和恢复这一物种.
by China Forestry Bureau(100714 Beijing   +1 more
doaj  

Distinct and contrasting transcription initiation patterns at Mycobacterium tuberculosis promoters. [PDF]

open access: yesPLoS ONE, 2012
Although sequencing of Mycobacterium tuberculosis genome lead to better understanding of transcription units and gene functions, interactions occurring during transcription initiation between RNA polymerase and promoters is yet to be elucidated ...
Priyanka Tare   +2 more
doaj   +1 more source

Shenzhen Workers Strike Again [PDF]

open access: yes, 2011
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Weekly News Brief [PDF]

open access: yes, 2012
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Effect of Dried Porcine Placenta on Growth Performance in Post-Weaning Pigs

open access: yesWalailak Journal of Science and Technology, 2011
The objective of this research was to investigate the effect of substituting fish meal with dried porcine placenta (DPP) on the growth performance in post-weaning pigs. The experimental animals included 25 males and 25 females.
China SUPAKORN, Siripen THONGPASSANO
doaj   +1 more source

CLW Labor News Brief for June 2015 [PDF]

open access: yes, 2015
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

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