Results 51 to 60 of about 8,992,180 (303)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Effect of Dried Porcine Placenta on Growth Performance in Post-Weaning Pigs

open access: yesWalailak Journal of Science and Technology, 2011
The objective of this research was to investigate the effect of substituting fish meal with dried porcine placenta (DPP) on the growth performance in post-weaning pigs. The experimental animals included 25 males and 25 females.
China SUPAKORN, Siripen THONGPASSANO
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Preface: Morphology and Internal Mixing of Atmospheric Particles

open access: yesAtmosphere, 2018
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Swarup China, Claudio Mazzoleni
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Genetic parameter estimates for weaning weight and Kleiber ratio in goats [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2012
The research was conducted to evaluate the factors affecting on weaning weight (WW) and Kleiber ratio (KR) and toestimate genetic parameters for two traits in goats.
China Supakorn, Winai Pralomkarn
doaj  

Trends in China's anthropogenic emissions since 2010 as the consequence of clean air actions

open access: yesAtmospheric Chemistry and Physics, 2018
. To tackle the problem of severe air pollution, China has implemented active clean air policies in recent years. As a consequence, the emissions of major air pollutants have decreased and the air quality has substantially improved.
B. Zheng   +15 more
semanticscholar   +1 more source

Modified SEIR and AI prediction of the epidemics trend of COVID-19 in China under public health interventions

open access: yesJournal of Thoracic Disease, 2020
Background The coronavirus disease 2019 (COVID-19) outbreak originating in Wuhan, Hubei province, China, coincided with chunyun, the period of mass migration for the annual Spring Festival.
Zi-feng Yang   +25 more
semanticscholar   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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