Results 51 to 60 of about 13,440,726 (353)

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Preface: Morphology and Internal Mixing of Atmospheric Particles

open access: yesAtmosphere, 2018
n ...
Swarup China, Claudio Mazzoleni
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Effect of Dried Porcine Placenta on Growth Performance in Post-Weaning Pigs

open access: yesWalailak Journal of Science and Technology, 2011
The objective of this research was to investigate the effect of substituting fish meal with dried porcine placenta (DPP) on the growth performance in post-weaning pigs. The experimental animals included 25 males and 25 females.
China SUPAKORN, Siripen THONGPASSANO
doaj   +1 more source

Deterioration of Mattel’s Labor Conditions: An Investigation of Four Factories – November 29, 2012 [PDF]

open access: yes, 2012
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch
core   +1 more source

Trends in China's anthropogenic emissions since 2010 as the consequence of clean air actions

open access: yesAtmospheric Chemistry and Physics, 2018
. To tackle the problem of severe air pollution, China has implemented active clean air policies in recent years. As a consequence, the emissions of major air pollutants have decreased and the air quality has substantially improved.
B. Zheng   +15 more
semanticscholar   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Stress corrosion behavior of X80 pipeline steel in the natural seawater with different dissolved oxygen contents

open access: yesFracture and Structural Integrity, 2019
Stress corrosion slow strain rate tensile tests of the X80 steel in the natural seawater are carried out to study the effect of dissolved oxygen (DO) on the sensitivity of stress corrosion.
Zhong-ying Han   +1 more
doaj   +1 more source

Foxconn Faces Another Strike [PDF]

open access: yes, 2013
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
China Labor Watch
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy