Results 71 to 80 of about 8,992,180 (303)

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Drivers of improved PM2.5 air quality in China from 2013 to 2017

Proceedings of the National Academy of Sciences of the United States of America, 2019
Significance The high frequency of haze pollution in China has attracted broad attention and triggered, in 2013, the promulgation of the toughest-ever clean air policy in the country.
Qiang Zhang, Yixuan Zheng, D. Tong, M. Shao, Shuxiao Wang, Yuanhang Zhang, Xiangde Xu, Jinnan Wang, Hong He, Wenqing Liu, Yihui Ding, Y. Lei, Junhua Li, Zifa Wang, Xiaoye Zhang, Yuesi Wang, Jing Cheng, Yang Liu, Q. Shi, Liu Yan, G. Geng, C. Hong, Meng Li, Fei Liu, B. Zheng, Junji Cao, A. Ding, Jian Gao, Q. Fu, Juntao Huo, Baoxian Liu, Zirui Liu, Fumo Yang, K. He, J. Hao   +34 more
semanticscholar   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Comparison of N uptake and internal use efficiency in two tobacco varieties

Crop Journal, 2015
To explain the observation in field experiments that tobacco variety CB-1 was more nitrogen (N)-efficient than K326, the influence of two N levels on growth, N uptake and N flow within plants of the two tobacco varieties was studied.
Department of Plant Nutrition, China Agricultural University, Beijing 100193, China, Wenqing Li , Chunjian Li    +2 more
doaj   +1 more source

Rural E‐commerce and County Economic Development in China [PDF]

, 2023
Qiuxia Qin, Hongdong Guo, Xinjie Shi, Kevin Z. Chen   +3 more
openalex   +1 more source

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Current cancer situation in China: good or bad news from the 2018 Global Cancer Statistics?

Cancer Communications, 2019
Cancer is the leading cause of death in China and depicting the cancer pattern of China would provide basic knowhows on how to tackle it more effectively.
Ruimei Feng, Yi-Nan Zong, Su-Mei Cao, R. Xu   +3 more
semanticscholar   +1 more source

Spatial-Temporal Responses of Ecosystem Services to Land Use Transformation Driven by Rapid Urbanization: A Case Study of Hubei Province, China [PDF]

, 2021
Xufeng Cui, Cuicui Liu, Ling Shan, Jiaqi Lin, Jing Zhang, Yuehua Jiang, Guanghong Zhang   +6 more
openalex   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source