Results 91 to 100 of about 2,907,472 (316)

Processing Chinese object-topicalization structures in simple and complex sentences

Linguistics
Chinese has the basic word order of Subject-Verb-Object (SVO), yet it is also known as a topic-prominent language, where an object can be topicalized from within a relative clause as well as from a main clause.
Wu Fuyun, Wang Fang, Li Jinman
doaj   +1 more source

Association between serum uric acid level and hypertension in a Chinese elderly rural population

Clinical and Experimental Hypertension, 2017
Previous studies have examined the association between elevated serum uric acid (SUA) level and hypertension; however, the association in the Chinese elderly is still uncertain. A cross-sectional study was performed in a rural district of Beijing.
Lei Wu, Yao He, Bin Jiang, Miao Liu, Jianhua Wang, Di Zhang, Yiyan Wang, Jing Zeng   +7 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Chinese Association of Greater Toledo newsletter, Spring 2007 [PDF]

, 2007
A newsletter published by the Chinese Association of Greater Toledo (CAGT). CAGT was founded in 1965 to support the Chinese community in and around Toledo, Ohio and uphold Chinese culture, language, and customs.
Chinese Association of Greater Toledo (Toledo, Ohio)
core  

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Chinese Association of Greater Toledo newsletter, Fall 2007 [PDF]

, 2007
A newsletter published by the Chinese Association of Greater Toledo (CAGT). CAGT was founded in 1965 to support the Chinese community in and around Toledo, Ohio and uphold Chinese culture, language, and customs.
Chinese Association of Greater Toledo (Toledo, Ohio)
core  

A Novel Missense Mutation in TWNK Gene Causing Perrault Syndrome Type 5 in a Chinese Family and Review of the Literature

Pharmacogenomics and Personalized Medicine, 2022
Lan Wei, Ling Hou, Yan-Qin Ying, Xiao-Ping Luo Department of Pediatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei, 430030, People’s Republic of ChinaCorrespondence: Yan-Qin YingDepartment of ...
Wei L, Hou L, Ying YQ, Luo XP
doaj  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Cognitive Frailty and 30-Day Mortality in a National Cohort of Older Chinese Inpatients

Clinical Interventions in Aging, 2021
Xiao-Ming Zhang,1,* Jing Jiao,1,* Chen Zhu,1 Na Guo,1 Ying Liu,1 Dongmei Lv,2 Hui Wang,3 Jingfen Jin,4 Xianxiu Wen,5 Shengxiu Zhao,6 Xin-Juan Wu,1 Tao Xu7 1Department of Nursing, Chinese Academy of Medical Sciences - Peking Union Medical College, Peking ...
Zhang XM, Jiao J, Zhu C, Guo N, Liu Y, Lv D, Wang H, Jin J, Wen X, Zhao S, Wu XJ, Xu T   +11 more
doaj  

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source