Results 161 to 170 of about 35,402 (277)
ABSTRACT Dielectric barrier discharge ionization (DBDI) sources, employing low‐temperature plasma, have emerged as sensitive and efficient ionization tools with various atmospheric pressure ionization processes. In this review, we summarize a historical overview of the development of DBDI, highlighting key principles of gas‐phase ion chemistry and the ...
Kseniya Dryahina+4 more
wiley +1 more source
Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke+3 more
wiley +1 more source
Supercomputing Multi-Ligand Modeling, Simulation, Wavelet Analysis and Surface Plasmon Resonance to Develop Novel Combination Drugs: A Case Study of Arbidol and Baicalein Against Main Protease of SARS-CoV-2. [PDF]
Li H+9 more
europepmc +1 more source
Cell Apoptosis and Glucocorticoid‐Induced Osteonecrosis
The review identifies glucocorticoid‐induced osteocyte/osteoblast apoptosis as central to femoral head osteonecrosis (GION), mediated through STAT1‐caspase‐3, PI3K/Akt, Wnt/β‐catenin, and oxidative stress pathways. Emerging therapies targeting these pathways (e.g., HIF‐1α stabilization, AMPK activation, and exosome‐mediated miRNA delivery) show ...
Xiumei Tang+7 more
wiley +1 more source
A perspective on the mechanisms of herbal medicine for cognitive impairment. [PDF]
Zheng SY, Zhou XQ.
europepmc +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro+5 more
wiley +1 more source
Network Pharmacology-Driven Sustainability: AI and Multi-Omics Synergy for Drug Discovery in Traditional Chinese Medicine. [PDF]
Yang L+6 more
europepmc +1 more source
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina+15 more
wiley +1 more source