Results 201 to 210 of about 70,878 (334)

Comprehensive Insights into Natural Bioactive Compounds: From Chemical Diversity and Mechanisms to Biotechnological Innovations and Applications

open access: yesChemistryOpen, EarlyView.
Natural products derived from plants, animals, fungi, bacteria, and minerals contain diverse bioactive classes such as alkaloids, flavonoids, terpenoids, saponins, tannins, and phenolics. These natural products work through different mechanisms, including ROS inhibition, NF‐κB suppression, and cytokine regulation, and exhibit wide applications across ...
Sajid Ali   +4 more
wiley   +1 more source

Celastrol, a Chinese herbal compound, controls autoimmune inflammation by altering the balance of pathogenic and regulatory T cells in the target organ

open access: bronze, 2015
Brian Astry   +7 more
openalex   +2 more sources

Playground tree diversity: A driver of well‐being in preschool children

open access: yesPeople and Nature, EarlyView.
Abstract Urban greenspaces benefit mental health in adults, with increasing evidence that biodiversity might also play a role. However, we know very little about the impact of urban biodiversity on preschool children's well‐being, despite the critical importance of the formative years.
Solène Guenat, Leonie K. Fischer
wiley   +1 more source

Optimizing Personalized Therapy for Rheumatoid Arthritis Using a Novel Drug Combination of Representative Bioactive Compounds of a Classic Chinese Herbal Formula

open access: green, 2018
Xia Mao   +10 more
openalex   +1 more source

Investigation of the Mechanism of Cinnamaldehyde in Irritable Bowel Syndrome Based via Network Pharmacology, Molecular Docking, and Animal Experiments

open access: yesPediatric Discovery, EarlyView.
Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu   +4 more
wiley   +1 more source

The ketogenic diet alters microbiome‐metabolome profiles to improve West syndrome therapy

open access: yesPediatric Investigation, EarlyView.
The ketogenic diet alleviates West syndrome by reshaping gut microbiota (increasing Bacteroides, Parabacteroides, and reducing Escherichia and Bifidobacterium), and modulating metabolites—including anticonvulsant lipids (e.g., capric acid), suppressed harmful lipids (e.g., 2‐methylbutyroylcarnitine), and amino acids and analogs (e.g., 3‐sulfinoalanine)—
Gan Xie   +5 more
wiley   +1 more source

Linking to images and AI‐based identification tools—The only way for Flora projects to survive

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Floras are comprehensive and authoritative catalogues of plants growing in an area of interest. They help people find and name plants, which is achieved by a combination of images, drawings, and text, rarely also maps. Like other catalogues (lexica, dictionaries, telephone books), Floras will not survive unless they move online and become portable ...
Susanne S. Renner
wiley   +1 more source

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