Results 71 to 80 of about 35,402 (277)

Identification of Natural Compound Carnosol as a Novel TRPA1 Receptor Agonist

Molecules, 2014
The transient receptor potential ankyrin 1 (TRPA1) cation channel is one of the well-known targets for pain therapy. Herbal medicine is a rich source for new drugs and potentially useful therapeutic agents.
Chenxi Zhai, Qing Liu, Yuxin Zhang, Shifeng Wang, Yanling Zhang, Shiyou Li, Yanjiang Qiao   +6 more
doaj   +1 more source

Antiviral effects and mechanism of Qi pi pill against influenza viruses

Animal Models and Experimental Medicine, EarlyView.
Qi pi pill presents anti‐influenza effect and inhibits viral replication in vitro by targeting both the viral RNA replication and the release of new viral particles. Furthermore, QPP modulates the production of proinflammatory cytokines induced by influenza infection in host cells.
Chengcheng Zhang, Jing Gao, Meiyue Dong, Carolina Q. Sacramento, Ping Li, Xiangyu Lian, Lingyuan Fan, Lijun Rong, Ruikun Du, Jingzhen Tian, Qinghua Cui   +10 more
wiley   +1 more source

A molecular docking study of Rhizoma Atractylodis and Rhizoma Atractylodis Macrocephalae herbal pair with respect to type 2 diabetes mellitus

Journal of Traditional Chinese Medical Sciences, 2018
Objective: To investigate the action mechanism of Rhizoma Atractylodis (Atractylodes lancea (Thunb.) Dc.) and Rhizoma Atractylodis Macrocephalae (Atractylodes macrocephala Koidz.), a two-herb ancient traditional Chinese medicine used to treat type 2 ...
Che Chen, Sheng Zhou, Qinggang Meng
doaj  

A High Content Screening Assay to Identify Compounds with Anti-Epithelial-Mesenchymal Transition Effects from the Chinese Herbal Medicine Tong-Mai-Yang-Xin-Wan

Molecules, 2016
Chronic kidney disease (CKD) is a worldwide health problem with growing prevalence in developing countries. Renal tubular epithelial-mesenchymal transition (EMT) is a critical step and key factor in the development of this condition.
Ningning Liu, Lailai Li, Xin Zhu, Zhiqiang Ling, Jianguo Feng, Ying Hu, Yi Wang, Lijun Mou, Yi Wang   +8 more
doaj   +1 more source

Brassinin from Brassica campestris L. inhibits colorectal cancer by inducing p62/NRF2/GPX4‐regulated ferroptosis

Animal Models and Experimental Medicine, EarlyView.
BSN suppresses the cell viability of colorectal cancer by inducing GPX4‐regulated ferroptosis. BSN may bind to NRF2 protein to inactivate the NRF2 signaling, inhibiting the expression of p62 and HO‐1. Abstract Background Indole phytoalexins, plant‐derived compounds present in cruciferous vegetables, have demonstrated anticancer properties.
Shi‐Yuan Wen, Rui‐Rui Gao, Yan‐Yan Chen, Yi‐Jie Wang, Xin‐Tong Wang, Hai‐Xin Liu   +5 more
wiley   +1 more source

Recent Progress on the Identification of Phenanthrene Derivatives in Traditional Chinese Medicine and Their Biological Activities

Pharmacological Research - Modern Chinese Medicine, 2022
In recent years, traditional Chinese medicines and active natural ingredients have been increasingly recognized for their medication effect worldwide. Phenanthrene derivatives, one of the main active ingredients in many Chinese herbal medicines such as ...
Jingyi Li, Wentao Feng, Rongji Dai, Bo Li   +3 more
doaj  

Survival Analysis of Traditional Chinese Herbal Medicine Spleen-invigorating Compound in Patients with Pancreatic cancer [PDF]

, 2020
Xin Li, Ling Chen, Xiaoqiang Gu, Jiahua Xu, Hongwei Li, Jinzu Yang, Jianxin Qian   +6 more
openalex   +1 more source

Yunweiling alleviates functional constipation: integrating network pharmacology and experimental study

Animal Models and Experimental Medicine, EarlyView.
In a study combining network pharmacological analysis and experimental verification, yunweiling has been shown improve functional constipation by inhibiting the PI3K‐Akt‐p53 signaling pathway and reducing the expression of TP53. Abstract Background This study investigated the impacts and mechanisms of yunweiling in the management of Functional ...
Peng Zhang, Wei Li, Weiwen Zheng, Jinwen Liu, Nuonan She, Xia Chen, Weibo Wen   +6 more
wiley   +1 more source

Targeting ferroptosis using Chinese herbal compounds to treat respiratory diseases

Phytomedicine
Respiratory diseases pose a grave threat to human life. Therefore, understanding their pathogenesis and therapeutic strategy is important. Ferroptosis is a novel type of iron-dependent programmed cell death, distinct from apoptosis, necroptosis, and autophagy, characterised by iron, reactive oxygen species, and lipid peroxide accumulation, as well as ...
Mengjiao Xu, Di Zhang, Jun Yan
openaire   +2 more sources

A comparative study of Salvia miltiorrhiza Radix & Rhizoma raw material and granule products using chromatographic analysis and antioxidant activity

Journal of Traditional Chinese Medical Sciences, 2022
Objective: Granules of herbal extracts are a popular medicinal preparation consumed in traditional Chinese medicine clinical practice. However, their quality and efficacy evaluation are lacking.
Xian Zhou, Valentina Razmovski-Naumovski, Raynold Mendoza, John Truong, Kelvin Chan   +4 more
doaj