Results 91 to 100 of about 6,696,208 (403)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Traditional Chinese medicine compound Erxian soup extract with menopausal cognitive function [PDF]

open access: yes, 2012
The invention relates to modern pharmacology research in traditional Chinese medicines, in particular to a traditional Chinese medicine compound Erxian soup extract with a menopausal cognitive function.

core  

Research advances on the anti-aging profile of Fructus lycii: An ancient Chinese herbal medicine [PDF]

open access: yes, 2008
Fructus lycii is a common Chinese herbal medicine used in China for nearly 2000 years. It has beneficial effects on eyes, liver and kidneys; and it has long been considered to be an anti-aging herb in ancient Chinese medicine.
Chang, RCC   +5 more
core   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Treatment efficacy analysis of traditional Chinese medicine for novel coronavirus pneumonia (COVID-19): an empirical study from Wuhan, Hubei Province, China

open access: yesChinese Medicine, 2020
Background A novel coronavirus was identified in December, 2019 in Wuhan, China, and traditional Chinese medicine (TCM) played an active role in combating the novel coronavirus pneumonia (NCP) caused by this fast-spreading virus COVID-19.
Erdan Luo   +7 more
semanticscholar   +1 more source

China: a Lecture Series, Fall 2009 [PDF]

open access: yes, 2009
Shigehisa Kuriyama Harvard University September 17, 2009 How Chinese and Western Medicine Became Strangely Similar: the Untold Story of the Modern Body Xueping Zhong Tufts University October 15, 2009 Contemporary Chinese Society through Popular ...
Center for International Education
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

La conception des maladies de tiédeur dans la médecine chinoise

open access: yesRevue d'anthropologie des connaissances, 2010
Since at least two thousand of years, Chinese medicine recognizes the role of abnormal climatic and environmental factors in the appearance of febrile diseases and in the emergence of epidemic outbreaks. Whereas they were mainly attributed in the past to
Dominique Buchillet
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Stratified therapy and adjuvant therapy with Chinese medicine for pneumonia patients with novel coronavirus infection

open access: yesDi-san junyi daxue xuebao, 2020
Combined with the existing literature and clinical guidelines, as well as our clinical experience, we stratified the pneumonia patients with novel coronavirus infection into light, common, heavy and critical types, who were given symptomatic treatment ...
LI Li   +6 more
doaj   +1 more source

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