Results 111 to 120 of about 6,696,208 (403)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Applications of Network Pharmacology in Traditional Chinese Medicine Research

Evidence-Based Complementary and Alternative Medicine, 2020
Human diseases, especially infectious ones, have been evolving constantly. However, their treatment strategies are not developing quickly. Some diseases are caused by a variety of factors with very complex pathologies, and the use of a single drug cannot
Zhuchen Zhou, Bing Chen, Simiao Chen, Minqiu Lin, Ying Chen, Shan Jin, Weiyan Chen, Yuyan Zhang   +7 more
semanticscholar   +1 more source

Contribution of traditional Chinese medicine combined with conventional western medicine treatment for the novel coronavirus disease (COVID‐19), current evidence with systematic review and meta‐analysis [PDF]

, 2021
Fei Jiang, Nana Xu, Yanxi Zhou, Jinxing Song, Jinjuan Liu, Hong Zhu, Jihong Jiang, Yonghong Xu, Rongpeng Li   +8 more
openalex   +1 more source

Chinese medicine treatment for menopausal symptoms in the UK health service: Is a clinical trial warranted? [PDF]

, 2014
Objectives The aims of this pilot study were to evaluate treatment effects, ascertain safety and formulate best practice Chinese medicine protocols relevant for London women suffering from menopausal symptoms.
Alraek, Borrelli, Borud, Chen, Davis, Dodin, Ganti, Greene, Hardie, Hilditch, Hirata, Kwee, Lakens, Liu, Lock, Ma, Maclennan, MacPherson, Mark Bovey, Meyer, Paterson, Posadzki, Preston, Price, Scheid, Scheid, Scheid, Scheid, Scheid, StatsToDo, Thomas, Thomas Weijburg, Timur, Trina Ward, van der Sluijs, Veronica Tuffrey, Volker Scheid, Ward, Williams, Witt, Witt, Xia, Zhong   +42 more
core   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Traditional Chinese Medicine and Its Role in Women’s Health [PDF]

, 2020
This paper is a literature review of traditional Chinese medicine and its role in women’s health. A search was performed and a group of 208 articles were initially found using the Liberty Summons search engine.
Smith, Ezekiel
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Guidelines for Echocardiographic Diagnosis of Cardiomyopathy: Recommendations from Echocardiography Group of Ultrasound Medicine Branch in Chinese Medical Association, Echocardiography Committee of Cardiovascular Branch in Chinese Medical Association [PDF]

Advanced Ultrasound in Diagnosis and Therapy, 2022
Echocardiography Group of Ultrasound Medicine Branch in Chinese Medical Association, Echocardiography Committee of Cardiovascular Branch in Chinese Medical Association
doaj   +1 more source

Cultural nourishment for the development of chinese medicine

Chinese Medicine and Culture, 2019
Medicine, especially traditional Chinese medicine, is by no means a single level of knowledge system and operational skills, but is full of humanistic color, encompassing natural science and social science, medical theory and traditional culture ...
Qizhong Li
doaj   +1 more source