Results 111 to 120 of about 604,881 (306)

Bioinformatic Analysis for Profiling Drug-induced Chromatin Modification Landscapes in Mouse Brain Using ChlP-seq Data

Bio-Protocol, 2017
Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a powerful technology to profile genome-wide chromatin modification patterns and is increasingly being used to study the molecular mechanisms of brain diseases such as ...
Yong-Hwee Loh, Jian Feng, Eric Nestler , Li Shen   +3 more
doaj   +1 more source

Lactiplantibacillus Plantarum GUANKE Alleviates Allergic Asthma by Restricting Monocyte‐to‐DC Differentiation Via Microbiota‐Associated IAA

Advanced Science, EarlyView.
Lactiplantibacillus plantarum GUANKE remodels the indigenous gut microbiota and is associated with microbiota‐dependent restoration of circulating IAA. IAA treatment attenuates JAK3‐STAT3 and Jag1‐Notch4‐Hey1 signaling and reduces CX3CR1+Ly6C− monocytic precursor generation and pulmonary CD11b+ DC accumulation, together with reduced Th2 inflammation ...
Yujia He, Jielan Mi, Zhiping Zhao, Xiao Zhang, Zhihan Yang, Kun Yue, Yuanming Huang, Liqiong Song, Xiaoting Wen, Jianguo Xu, Zhihong Ren   +10 more
wiley   +1 more source

ChIP-seq bigwig files

ChIP-seq of Pygo2,H3K4me3, p53 ...
Sheng Liu (12728327)
core   +1 more source

Perm-seq analysis of GM12878 Ctcf and Sin3a ChIP-seq dataset with DNase-seq and Histone ChIP-seq priors.

, 2015
(a) Heatmap of normalized DNase-seq and Histone ChIP-seq read counts for the [-1000 bps, +1000 bps] window anchored at GM12878 Ctcf peak summits depicted by the vertical dashed lines.
Constanza Rojo (816204), Ye Zheng (169955), Rene Welch (816203), Xin Zeng (174828), Sündüz Keleş (3436304), Bo Li (112195), Colin N. Dewey (257084)   +6 more
core   +1 more source

Loss of E3 Ubiquitin Ligase RINES via CpG Methylation Relieves Suppression of STAT3 and MYC, Facilitating Multiple Tumorigeneses

Advanced Science, EarlyView.
Dysregulated protein modifications drive tumorigenesis. RINES, an E3 ubiquitin ligase, represses tumor cell proliferation and metastasis by facilitating RING domain‐dependent, ubiquitin–proteasome‐mediated degradation of STAT3 and MYC, which consequently restrains cancer stemness and oncogenic progression.
Lili Li, Ka Man Ng, Xingsheng Shu, Xiaoxue Chai, Kai Yau Wong, Gopesh Srivastava, Anthony T.C. Chan, Wai Yee Chan, Qian Tao   +8 more
wiley   +1 more source

Expresso: A database and web server for exploring the interaction of transcription factors and their target genes in Arabidopsis thaliana using ChIP-Seq peak data [version 1; referees: 2 approved, 1 approved with reservations]

F1000Research, 2017
Motivation: The increasing availability of chromatin immunoprecipitation sequencing (ChIP-Seq) data enables us to learn more about the action of transcription factors in the regulation of gene expression.
Delasa Aghamirzaie, Karthik Raja Velmurugan, Shuchi Wu, Doaa Altarawy, Lenwood S. Heath, Ruth Grene   +5 more
doaj   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Chromatin immunoprecipitation (ChIP) of plant transcription factors followed by sequencing (ChIP-SEQ) or hybridization to whole genome arrays (ChIP-CHIP)

, 2010
Chromatin immunoprecipitation (ChIP) is a powerful technique to study interactions between transcription factors (TFs) and DNA in vivo. For genome-wide de novo discovery of TF-binding sites, the DNA that is obtained in ChIP experiments needs to be ...
Angenent, G.C., Farinelli, L., Østerås, M., Krajewski, P., Muiño, J.M., Kaufmann, K.   +5 more
core   +1 more source

ChIP-seq analysis from ZEB1 and ZEB2 in GM12878 and K562 cell lines, respectively in 2 different ChIP-seq experiments (GEO accessions GSE32465 and GSE59395, respectively).

, 2021
We calculated 1× normalized occupancy values in a window of 4000 base pairs around genes containing peaks that also are DEGs in the mouse (see S1 Table). Peak annotation was performed with the ChIPSeeker R package. ChIP-seq, Chromatin Immunoprecipitation
Jose M. Polo (8923700), Thomas Brabletz (517809), Christian M. Nefzger (11017494), Catherine Carmichael (54191), Danny Huylebroeck (124349), Katharina Haigh (58906), Aissa Benyoucef (11467508), Carlos Farkas (455344), Nick Wong (11467511), Jueqiong Wang (11467505), Marc P. Stemmler (11467514), Simone Brabletz (9905325), Geert Berx (12850), Jody J. Haigh (10999212), Steven Goossens (426910)   +14 more
core   +1 more source

The ChIP-Seq tools and web server: a resource for analyzing ChIP-seq and other types of genomic data

BMC Genomics, 2016
ChIP-seq and related high-throughput chromatin profilig assays generate ever increasing volumes of highly valuable biological data. To make sense out of it, biologists need versatile, efficient and user-friendly tools for access, visualization and itegrative analysis of such data.Here we present the ChIP-Seq command line tools and web server ...
Giovanna Ambrosini, René Dreos, Sunil Kumar, Philipp Bucher   +3 more
openaire   +4 more sources