Results 121 to 130 of about 103,657 (215)

ChIP-Seq Analysis of SlAREB1 Downstream Regulatory Network during Tomato Ripening. [PDF]

Foods, 2023
He Y, Wu Q, Cui C, Tian Q, Zhang D, Zhang Y.   +5 more
europepmc   +1 more source

Lactoferrin Deficiency During Lactation Causes Adult Obesity‐Related Metabolic Disease Through Persistent Adipose Dysfunction Driven by Impaired Adipocyte Development

Advanced Science, EarlyView.
Lactational lactoferrin deficiency exerts lasting effects on epididymal adipose tissue development from lactation into adulthood: it impairs adipocyte hyperplasia and induces pathological hypertrophy, resulting in lower body weight yet exacerbated metabolic dysfunction under a high‐fat diet in adulthood.
Qin An, Yunxia Zou, Wenli Wang, Zhimei Cheng, Zhuoxing Zhang, Ruwei Liu, Xiong Wang, Kunlun Huang, Fangrong Ding, Yunping Dai, Qingyong Meng, Yali Zhang   +11 more
wiley   +1 more source

Chromatin landscape, transcriptomic and ChIP-seq profiling of Anopheles stephensi MSQ43 cell line. [PDF]

Sci Data
Lukyanchikova V, Nuriddinov M, Khabarova A, Gridina M, Popov A, Belokopytova P, Sharakhov IV, Fishman V.   +7 more
europepmc   +1 more source

Broadly Applicable Control Approaches Improve Accuracy of ChIP-Seq Data. [PDF]

Int J Mol Sci, 2023
Petrie MV, He Y, Gan Y, Ostrow AZ, Aparicio OM.   +4 more
europepmc   +1 more source

Targeting ANGPTL3 and IL‐33/ST2 Ameliorates Diabetic Kidney Disease by Reducing Lipotoxicity, Alleviating Inflammation and Inhibiting Fibrosis

Advanced Science, EarlyView.
Dual targeting of ANGPTL3 and IL‐33/ST2 attenuates diabetic kidney disease by reprogramming lipid–inflammatory crosstalk. This strategy reduces renal lipotoxicity, suppresses inflammatory activation, and limits fibrotic remodeling, thereby preserving kidney structure and function and highlighting a mechanism‐guided therapeutic approach for metabolic ...
Zhuojin Li, Zhonglian Cao, Rongrui Zhou, Xu Cheng, Xiaozhi Hu, Shuwen Xu, Zihan Dou, Ling Du, Dianwen Ju   +8 more
wiley   +1 more source

Selecting ChIP-seq normalization methods from the perspective of their technical conditions. [PDF]

Brief Bioinform
Colando S, Schulz D, Hardin J.
europepmc   +1 more source

CATCH-UP: A High-Throughput Upstream-Pipeline for Bulk ATAC-Seq and ChIP-Seq Data. [PDF]

J Vis Exp, 2023
Riva SG, Georgiades E, Gur ER, Baxter M, Hughes JR.   +4 more
europepmc   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Protocol for double-crosslinking ChIP-seq to improve data quality and enhance detection of challenging chromatin targets. [PDF]

STAR Protoc
Bao Y, Cacioppo R, Crisp A, Shlamovitz I, Sale JE, Tufegdzic Vidakovic A, Vervoort SJ, Zeller A.   +7 more
europepmc   +1 more source

peaksat: an R package for ChIP-seq peak saturation analysis. [PDF]

BMC Genomics, 2023
Boyd JR, Gao C, Quinn K, Fritz A, Stein J, Stein G, Glass K, Frietze S.   +7 more
europepmc   +1 more source