Results 81 to 90 of about 673,559 (305)

Chemical Screening Identifies Danofloxacin as a Self‐Renewal Agonist of Embryonic Stem Cells through Alleviation of HDAC1‐Mediated Deacetylation of Tert and Prdm10

open access: yesAdvanced Science, EarlyView.
This study identified Danofloxacin as a novel supporter of the maintenance of mouse embryonic stem cell (ESC) pluripotency. It functions partially by inhibiting HDAC1, which increases specific histone acetylation marks and activates key genes like Tert and Prdm10.
Yan Zhang   +8 more
wiley   +1 more source

vanrooij-lab/chip-seq-pipeline2: chip-seq-pipeline2

open access: yes
<p>chip-seq-pipeline2</p ...
Jin wook Lee, Soo Lee, J. Seth Strattan
core   +1 more source

7C: Computational Chromosome Conformation Capture by Correlation of ChIP-seq at CTCF motifs

open access: yesBMC Genomics, 2019
Background Knowledge of the three-dimensional structure of the genome is necessary to understand how gene expression is regulated. Recent experimental techniques such as Hi-C or ChIA-PET measure long-range chromatin interactions genome-wide but are ...
Jonas Ibn-Salem   +1 more
doaj   +1 more source

ChIP-Seq of ZmSNAC1, ZmNAC23 and ZmNAC20

open access: yes, 2019
To explore the function of ZmSNAC1, ZmNAC23 and ZmNAC20 in salt stress resistance and plant development, the downstream target genes were explored by ChIP-Seq with ZmNACs-GFP transgenic maize plants (pooled leaves and roots at V1 stage)
can liu (4453648)
core   +1 more source

CD9+ B Cells Induce T Follicular Helper Cell Apoptosis to Regulate Germinal Center Regression

open access: yesAdvanced Science, EarlyView.
A unique subset of CD9+ B cells regulates germinal center B (GC‐B) cell regression by inducing T follicular helper (Tfh) cell apoptosis through multiple signaling pathways, such as ALCAM‐CD6. FOXP1 plays a key role in GC‐B cell differentiation. These findings clarify mechanisms of GC degeneration and termination and offer potential targets for adenoid ...
Wenjing Liao   +27 more
wiley   +1 more source

ChIP-chip versus ChIP-seq: Lessons for experimental design and data analysis

open access: yesBMC Genomics, 2011
Background Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows genome-wide discovery of protein-DNA interactions such as transcription factor bindings and histone ...
Karchenko Peter V   +5 more
doaj   +1 more source

vanrooij-lab/chip-seq-pipeline2: timmer-et-al-2024

open access: yes
<p>Scripts chip-seq pipeline used for Timmer et al.
Jin wook Lee, Soo Lee, J. Seth Strattan
core   +1 more source

ChIPseqRUs: A pipeline for ChIP-seq preprocessing

open access: yes, 2016
<p>A preprocessing pipeline for ChIP-seq, including alignment, quality control, and visualization.</p ...
Loh, Yong-Hwee (5265370)   +5 more
core   +1 more source

DataSheet1_CSSQ: a ChIP-seq signal quantifier pipeline.pdf

open access: yes, 2023
Chromatin immunoprecipitation followed by sequencing (ChIP-seq) has revolutionized the studies of epigenomes and the massive increase in ChIP-seq datasets calls for robust and user-friendly computational tools for quantitative ChIP-seq. Quantitative ChIP-
Yajun Mei (12446586)   +3 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

open access: yesAdvanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao   +7 more
wiley   +1 more source

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